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Applying a high-throughput fluorescence polarization assay for the discovery of chemical probes blocking La:RNA interactions in vitro and in cells.
Sommer, Gunhild; Fedarovich, Alena; Kota, Venkatesh; Rodriguez, Reycel; Smith, Charles D; Heise, Tilman.
Afiliação
  • Sommer G; Medical University of South Carolina, Department of Biochemistry & Molecular Biology, 173 Ashley Avenue, Charleston, SC, United States of America.
  • Fedarovich A; Medical University of South Carolina, Department of Biochemistry & Molecular Biology, 173 Ashley Avenue, Charleston, SC, United States of America.
  • Kota V; Medical University of South Carolina, Department of Biochemistry & Molecular Biology, 173 Ashley Avenue, Charleston, SC, United States of America.
  • Rodriguez R; Medical University of South Carolina, Department of Biochemistry & Molecular Biology, 173 Ashley Avenue, Charleston, SC, United States of America.
  • Smith CD; Department of Pharmaceutical and Biomedical Sciences, 173 Ashley Avenue, Charleston, SC, United States of America.
  • Heise T; Medical University of South Carolina, Department of Biochemistry & Molecular Biology, 173 Ashley Avenue, Charleston, SC, United States of America.
PLoS One ; 12(3): e0173246, 2017.
Article em En | MEDLINE | ID: mdl-28291789
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA / Sondas Moleculares / Proteínas de Ligação a RNA / Ensaios de Triagem em Larga Escala / Polarização de Fluorescência Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA / Sondas Moleculares / Proteínas de Ligação a RNA / Ensaios de Triagem em Larga Escala / Polarização de Fluorescência Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article