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A Study on CYP2C19 and CYP2D6 Polymorphic Effects on Pharmacokinetics and Pharmacodynamics of Amitriptyline in Healthy Koreans.
Ryu, S; Park, S; Lee, J H; Kim, Y R; Na, H S; Lim, H S; Choi, H Y; Hwang, I Y; Lee, J G; Park, Z W; Oh, W Y; Kim, J M; Choi, S E.
Afiliação
  • Ryu S; Clinical Research Division, National Institute of Food and Drug Safety, Ministry of Food and Drug Safety, Republic of Korea.
  • Park S; Clinical Research Division, National Institute of Food and Drug Safety, Ministry of Food and Drug Safety, Republic of Korea.
  • Lee JH; Clinical Research Division, National Institute of Food and Drug Safety, Ministry of Food and Drug Safety, Republic of Korea.
  • Kim YR; Clinical Research Division, National Institute of Food and Drug Safety, Ministry of Food and Drug Safety, Republic of Korea.
  • Na HS; Clinical Research Division, National Institute of Food and Drug Safety, Ministry of Food and Drug Safety, Republic of Korea.
  • Lim HS; Department of Clinical Pharmacology and Therapeutics, College of Medicine, University of Ulsan, Asan Medical Center, Republic of Korea.
  • Choi HY; Department of Clinical Pharmacology and Therapeutics, College of Medicine, University of Ulsan, Asan Medical Center, Republic of Korea.
  • Hwang IY; Clinical Research Division, National Institute of Food and Drug Safety, Ministry of Food and Drug Safety, Republic of Korea.
  • Lee JG; Clinical Research Division, National Institute of Food and Drug Safety, Ministry of Food and Drug Safety, Republic of Korea.
  • Park ZW; Clinical Research Division, National Institute of Food and Drug Safety, Ministry of Food and Drug Safety, Republic of Korea.
  • Oh WY; Clinical Research Division, National Institute of Food and Drug Safety, Ministry of Food and Drug Safety, Republic of Korea.
  • Kim JM; Clinical Research Division, National Institute of Food and Drug Safety, Ministry of Food and Drug Safety, Republic of Korea.
  • Choi SE; Clinical Research Division, National Institute of Food and Drug Safety, Ministry of Food and Drug Safety, Republic of Korea.
Clin Transl Sci ; 10(2): 93-101, 2017 03.
Article em En | MEDLINE | ID: mdl-28296334
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polimorfismo Genético / Inibidores da Captação Adrenérgica / Citocromo P-450 CYP2D6 / Citocromo P-450 CYP2C19 / Amitriptilina / Antidepressivos Tricíclicos / Nortriptilina Tipo de estudo: Clinical_trials / Guideline Limite: Adult / Humans / Male País/Região como assunto: Asia Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polimorfismo Genético / Inibidores da Captação Adrenérgica / Citocromo P-450 CYP2D6 / Citocromo P-450 CYP2C19 / Amitriptilina / Antidepressivos Tricíclicos / Nortriptilina Tipo de estudo: Clinical_trials / Guideline Limite: Adult / Humans / Male País/Região como assunto: Asia Idioma: En Ano de publicação: 2017 Tipo de documento: Article