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The development of novel LTA4H modulators to selectively target LTB4 generation.
Low, Caroline M; Akthar, Samia; Patel, Dhiren F; Löser, Stephan; Wong, Chi-Tung; Jackson, Patricia L; Blalock, J Edwin; Hare, Stephen A; Lloyd, Clare M; Snelgrove, Robert J.
Afiliação
  • Low CM; Computational Drug Design Consultant, Dulwich, London SE21 8LS, United Kingdom.
  • Akthar S; Inflammation Repair and Development, National Heart and Lung Institute, Imperial College London, London SW7 2AZ, United Kingdom.
  • Patel DF; Inflammation Repair and Development, National Heart and Lung Institute, Imperial College London, London SW7 2AZ, United Kingdom.
  • Löser S; Inflammation Repair and Development, National Heart and Lung Institute, Imperial College London, London SW7 2AZ, United Kingdom.
  • Wong CT; Department of Life Sciences, Imperial College London, London SW7 2AZ, United Kingdom.
  • Jackson PL; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
  • Blalock JE; Birmingham V.A. Medical Center, Birmingham, AL 35294, USA.
  • Hare SA; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
  • Lloyd CM; Department of Life Sciences, Imperial College London, London SW7 2AZ, United Kingdom.
  • Snelgrove RJ; Inflammation Repair and Development, National Heart and Lung Institute, Imperial College London, London SW7 2AZ, United Kingdom.
Sci Rep ; 7: 44449, 2017 03 17.
Article em En | MEDLINE | ID: mdl-28303931

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucotrieno B4 / Inibidores Enzimáticos / Epóxido Hidrolases / Anti-Inflamatórios / Neutrófilos Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucotrieno B4 / Inibidores Enzimáticos / Epóxido Hidrolases / Anti-Inflamatórios / Neutrófilos Idioma: En Ano de publicação: 2017 Tipo de documento: Article