Fluorinated PET Tracers for Molecular Imaging of &#963;<sub>1</sub> Receptors in the Central Nervous System.

Weber, Frauke; Brust, Peter; Laurini, Erik; Pricl, Sabrina; Wünsch, Bernhard

Fluorinated PET Tracers for Molecular Imaging of σ₁ Receptors in the Central Nervous System.

Weber, Frauke; Brust, Peter; Laurini, Erik; Pricl, Sabrina; Wünsch, Bernhard.

Afiliação

Weber F; Institute of Pharmaceutical and Medicinal Chemistry, Westfälische Wilhelms-Universität Münster, Corrensstraße 48, D-48149, Münster, Germany.
Brust P; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Permoserstraße 15, D-04318, Leipzig, Germany.
Laurini E; Molecular Simulations Engineering (MOSE) Laboratory, Department of Engineering and Architecture (DEA), University of Trieste, Via Valerio 6, 34127, Trieste, Italy.
Pricl S; Molecular Simulations Engineering (MOSE) Laboratory, Department of Engineering and Architecture (DEA), University of Trieste, Via Valerio 6, 34127, Trieste, Italy.
Wünsch B; National Interuniversity Consortium for Material Science and Technology (INSTM), Research Unit MOSE-DEA, University of Trieste, Via Valerio 6, 32127, Trieste, Italy.

Adv Exp Med Biol ; 964: 31-48, 2017.

Article em En | MEDLINE | ID: mdl-28315263

Assuntos

Sistema Nervoso Central/metabolismo; Receptores sigma/metabolismo; Animais; Radioisótopos de Flúor/metabolismo; Imagem Molecular/métodos; Tomografia por Emissão de Pósitrons/métodos; Compostos Radiofarmacêuticos/metabolismo; Receptor Sigma-1

Palavras-chave

Enantioselective kinetics; Ligand receptor interaction; Neuroimaging; Non-covalent quasi irreversible binding; PET , synthesis; Radiosynthesis; σ1 receptors

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistema Nervoso Central / Receptores sigma Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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