Tetrahydro-2-furanyl-2,4(1H,3H)-pyrimidinedione derivatives as novel antibacterial compounds against <i>Mycobacterium</i>.

Koseki, Yuji; Kanetaka, Hironori; Tsunosaki, Joji; Munier-Lehmann, Héléne; Aoki, Shunsuke

Tetrahydro-2-furanyl-2,4(1H,3H)-pyrimidinedione derivatives as novel antibacterial compounds against Mycobacterium.

Koseki, Yuji; Kanetaka, Hironori; Tsunosaki, Joji; Munier-Lehmann, Héléne; Aoki, Shunsuke.

Afiliação

Koseki Y; Department of Bioscience and Bioinformatics, Graduate School of Computer Science and Systems Engineering, Kyushu Institute of Technology, 680-4 Kawazu, Iizuka-shi, Fukuoka 820-8502, Japan.
Kanetaka H; Department of Bioscience and Bioinformatics, Graduate School of Computer Science and Systems Engineering, Kyushu Institute of Technology, 680-4 Kawazu, Iizuka-shi, Fukuoka 820-8502, Japan.
Tsunosaki J; Department of Bioscience and Bioinformatics, Graduate School of Computer Science and Systems Engineering, Kyushu Institute of Technology, 680-4 Kawazu, Iizuka-shi, Fukuoka 820-8502, Japan.
Munier-Lehmann H; Institut Pasteur, Unite de Chimie et Biocatalyse, Departement de Biologie Structurale et Chimie, 28 rue du Dr Roux, F-75015; CNRS, UMR3523, F-75015 Paris, France.
Aoki S; Department of Bioscience and Bioinformatics, Graduate School of Computer Science and Systems Engineering, Kyushu Institute of Technology, 680-4 Kawazu, Iizuka-shi, Fukuoka 820-8502, Japan; Biomedical Informatics Research and Development Center, Kyushu Institute of Technology, 680-4 Kawazu, Iizuka-sh

Int J Mycobacteriol ; 6(1): 61-69, 2017.

Article em En | MEDLINE | ID: mdl-28317807

Assuntos

Antituberculosos/farmacologia; Furanos/farmacologia; Mycobacterium smegmatis/efeitos dos fármacos; Núcleosídeo-Fosfato Quinase/antagonistas & inibidores; Pirimidinonas/farmacologia; Antituberculosos/química; Simulação por Computador; Descoberta de Drogas; Furanos/química; Ensaios de Triagem em Larga Escala; Testes de Sensibilidade Microbiana; Modelos Moleculares; Mycobacterium smegmatis/crescimento & desenvolvimento; Mycobacterium tuberculosis/efeitos dos fármacos; Pirimidinonas/química; Relação Estrutura-Atividade; Tuberculose/tratamento farmacológico

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinonas / Núcleosídeo-Fosfato Quinase / Mycobacterium smegmatis / Furanos / Antituberculosos Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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