Moraxella Species as Potential Sources of MCR-Like Polymyxin Resistance Determinants.

Kieffer, Nicolas; Nordmann, Patrice; Poirel, Laurent

Kieffer, Nicolas; Nordmann, Patrice; Poirel, Laurent.

Afiliação

Kieffer N; Emerging Antibiotic Resistance, Medical and Molecular Microbiology Unit, Department of Medicine, University of Fribourg, Fribourg, Switzerland.
Nordmann P; INSERM European Unit (IAME, France), University of Fribourg, Fribourg, Switzerland.
Poirel L; Emerging Antibiotic Resistance, Medical and Molecular Microbiology Unit, Department of Medicine, University of Fribourg, Fribourg, Switzerland.

Antimicrob Agents Chemother ; 61(6)2017 06.

Article em En | MEDLINE | ID: mdl-28320720

ABSTRACT

ABSTRACT

Plasmid-mediated resistance to polymyxins mediated by the MCR-1/2 determinants has been reported in Enterobacteriaceae worldwide. Using PCR-based and cloning strategies, a series of Moraxella spp. were screened for mcr-like genes. Moraxella spp. that are mainly animal pathogens but may also be human pathogens were identified as potential reservoirs of mcr-like genes.

Assuntos

Antibacterianos/farmacologia; Etanolaminofosfotransferase/genética; Moraxella/efeitos dos fármacos; Infecções por Moraxellaceae/tratamento farmacológico; Polimixinas/farmacologia; Animais; Farmacorresistência Bacteriana; Moraxella/genética; Moraxella/isolamento & purificação; Infecções por Moraxellaceae/microbiologia; Plasmídeos/genética

Palavras-chave

MCR; animal; plasmid; polymyxin; reservoir; resistance

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polimixinas / Infecções por Moraxellaceae / Etanolaminofosfotransferase / Antibacterianos / Moraxella Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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