Your browser doesn't support javascript.
loading
Somatic mutations reveal asymmetric cellular dynamics in the early human embryo.
Ju, Young Seok; Martincorena, Inigo; Gerstung, Moritz; Petljak, Mia; Alexandrov, Ludmil B; Rahbari, Raheleh; Wedge, David C; Davies, Helen R; Ramakrishna, Manasa; Fullam, Anthony; Martin, Sancha; Alder, Christopher; Patel, Nikita; Gamble, Steve; O'Meara, Sarah; Giri, Dilip D; Sauer, Torril; Pinder, Sarah E; Purdie, Colin A; Borg, Åke; Stunnenberg, Henk; van de Vijver, Marc; Tan, Benita K T; Caldas, Carlos; Tutt, Andrew; Ueno, Naoto T; van 't Veer, Laura J; Martens, John W M; Sotiriou, Christos; Knappskog, Stian; Span, Paul N; Lakhani, Sunil R; Eyfjörd, Jórunn Erla; Børresen-Dale, Anne-Lise; Richardson, Andrea; Thompson, Alastair M; Viari, Alain; Hurles, Matthew E; Nik-Zainal, Serena; Campbell, Peter J; Stratton, Michael R.
Afiliação
  • Ju YS; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.
  • Martincorena I; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.
  • Gerstung M; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.
  • Petljak M; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.
  • Alexandrov LB; European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton CB10 1SD, UK.
  • Rahbari R; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.
  • Wedge DC; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.
  • Davies HR; Theoretical Biology and Biophysics (T-6), Los Alamos National Laboratory, Los Alamos, New Mexico 87545, USA.
  • Ramakrishna M; Genomic Mutation and Genetic Disease, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Fullam A; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.
  • Martin S; Oxford Big Data Institute and Oxford Centre for Cancer Gene Research, Wellcome Trust Centre for Human Genetics, Oxford, UK.
  • Alder C; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.
  • Patel N; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.
  • Gamble S; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.
  • O'Meara S; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.
  • Giri DD; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.
  • Sauer T; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.
  • Pinder SE; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.
  • Purdie CA; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.
  • Borg Å; Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
  • Stunnenberg H; Institute of Clinical Medicine, Campus at Akershus University Hospital, University of Oslo, Lørenskog, Norway.
  • van de Vijver M; King's Health Partners Cancer Biobank, Guy's Hospital, King's College London School of Medicine, London, UK.
  • Tan BK; Department of Pathology, Ninewells Hospital and Medical School, Dundee, UK.
  • Caldas C; BioCare, Strategic Cancer Research Program, Lund, Sweden.
  • Tutt A; CREATE Health, Strategic Centre for Translational Cancer Research, Lund, Sweden.
  • Ueno NT; Department of Oncology and Pathology, Lund University Cancer Center, Lund, Sweden.
  • van 't Veer LJ; Radboud University Medical Center, Nijmegen, The Netherlands.
  • Martens JW; Department of Pathology, Academic Medical Center, Amsterdam, The Netherlands.
  • Sotiriou C; SingHealth Duke-NUS Breast Centre, Division of Surgical Oncology, National Cancer Centre Singapore, Department of General Surgery, Singapore General Hospital, Singapore.
  • Knappskog S; Cancer Research UK (CRUK) Cambridge Institute, University of Cambridge, Cambridge, UK.
  • Span PN; Breast Cancer Now Research Unit, King's College London, London SE1 9RT, UK.
  • Lakhani SR; Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, London SW3 6JB, UK.
  • Eyfjörd JE; Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Børresen-Dale AL; Department of Laboratory Medicine, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, USA.
  • Richardson A; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, Netherlands.
  • Thompson AM; Institut Jules Bordet, Brussels, Belgium.
  • Viari A; Section of Oncology, Department of Clinical Science, University of Bergen, Bergen, Norway.
  • Hurles ME; Department of Oncology, Haukeland University Hospital, Bergen, Norway.
  • Nik-Zainal S; Department of Radiation Oncology and Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, Netherlands.
  • Campbell PJ; University of Queensland, School of Medicine, Brisbane, Australia.
  • Stratton MR; Pathology Queensland, Royal Brisbane and Women's Hospital, Brisbane, Australia.
Nature ; 543(7647): 714-718, 2017 03 30.
Article em En | MEDLINE | ID: mdl-28329761
Assuntos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenvolvimento Embrionário / Embrião de Mamíferos / Mutação Tipo de estudo: Prognostic_studies Limite: Adult / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenvolvimento Embrionário / Embrião de Mamíferos / Mutação Tipo de estudo: Prognostic_studies Limite: Adult / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article