Critical role of STIR MRI in early detection of post-streptococcal periostitis with dysproteinaemia (Goldbloom's syndrome).
Clin Exp Rheumatol
; 35(3): 516-517, 2017.
Article
em En
| MEDLINE
| ID: mdl-28339360
ABSTRACT
OBJECTIVES:
In 1966, Goldbloom et al. described two children who developed a peculiar clinical picture characterized by intermittent daily bone pain in the lower limbs, fever spikes, increased acute phase reactants and dysproteinaemia. The syndrome occurred two weeks after a group A ß-haemolytic streptococcus infection. So far, only a few cases have been reported in the medical literature in English.METHODS:
We report two further cases of Goldbloom's syndrome with a review of the literature in English.RESULTS:
Our two patients lived in the same Italian region and presented their syndrome onset a week apart. Early use of STIR MRI revealed an atypical metaphyseal hyperintensity in the femurs and tibias. X-ray showed periosteal hyperostosis. A short cycle of corticosteroids led to rapid recovery of symptoms and disappearance of bone changes.CONCLUSIONS:
The reported cases highlight a likely under-recognised post-streptococcal inflammatory periosteal reaction and emphasise the diagnostic utility of the newer imaging modalities.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Periostite
/
Infecções Estreptocócicas
/
Tíbia
/
Imageamento por Ressonância Magnética
/
Hipoalbuminemia
/
Fêmur
/
Hipergamaglobulinemia
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
/
Screening_studies
Limite:
Child
/
Female
/
Humans
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article