Therapeutic implication of 'Iturin A' for targeting MD-2/TLR4 complex to overcome angiogenesis and invasion.

Dey, Goutam; Bharti, Rashmi; Ojha, Probir Kumar; Pal, Ipsita; Rajesh, Y; Banerjee, Indranil; Banik, Payel; Parida, Sheetal; Parekh, Aditya; Sen, Ramkrishna; Mandal, Mahitosh

Dey, Goutam; Bharti, Rashmi; Ojha, Probir Kumar; Pal, Ipsita; Rajesh, Y; Banerjee, Indranil; Banik, Payel; Parida, Sheetal; Parekh, Aditya; Sen, Ramkrishna; Mandal, Mahitosh.

Afiliação

Dey G; School of Medical Science & Technology, Indian Institute of Technology Kharagpur, Kharagpur 721302, India.
Bharti R; School of Medical Science & Technology, Indian Institute of Technology Kharagpur, Kharagpur 721302, India.
Ojha PK; Drug Theoretics and Cheminformatics Laboratory, Division of Medicinal and Pharmaceutical Chemistry, Department of Pharmaceutical Technology, Jadavpur University, Kolkata 700032, India.
Pal I; School of Medical Science & Technology, Indian Institute of Technology Kharagpur, Kharagpur 721302, India.
Rajesh Y; School of Medical Science & Technology, Indian Institute of Technology Kharagpur, Kharagpur 721302, India.
Banerjee I; Division of Nuclear Medicine, Indian Institute of Chemical Biology, Kolkata 700032, West Bengal, India.
Banik P; School of Medical Science & Technology, Indian Institute of Technology Kharagpur, Kharagpur 721302, India.
Parida S; School of Medical Science & Technology, Indian Institute of Technology Kharagpur, Kharagpur 721302, India.
Parekh A; School of Medical Science & Technology, Indian Institute of Technology Kharagpur, Kharagpur 721302, India.
Sen R; Department of Biotechnology, Indian Institute of Technology Kharagpur, Kharagpur 721302, India. Electronic address: rksen@yahoo.com.
Mandal M; School of Medical Science & Technology, Indian Institute of Technology Kharagpur, Kharagpur 721302, India. Electronic address: mahitosh@smst.iitkgp.ernet.in.

Cell Signal ; 35: 24-36, 2017 07.

Article em En | MEDLINE | ID: mdl-28347875

Assuntos

Antígeno 96 de Linfócito/genética; Neoplasias/tratamento farmacológico; Neovascularização Patológica/tratamento farmacológico; Peptídeos Cíclicos/administração & dosagem; Receptor 4 Toll-Like/genética; Bacillus megaterium/química; Linhagem Celular Tumoral; Regulação Neoplásica da Expressão Gênica/efeitos dos fármacos; Células Endoteliais da Veia Umbilical Humana; Humanos; Quinase I-kappa B/genética; Antígeno 96 de Linfócito/química; Fator 88 de Diferenciação Mieloide/genética; NF-kappa B/genética; Invasividade Neoplásica/genética; Neoplasias/genética; Neoplasias/patologia; Neovascularização Patológica/genética; Neovascularização Patológica/patologia; Peptídeos Cíclicos/química; RNA Interferente Pequeno/genética; Transdução de Sinais/efeitos dos fármacos; Receptor 4 Toll-Like/química

Palavras-chave

Invasion; MD-2 (myeloid differentiation factor 2); TLR4; Tumor angiogenesis; Vascular endothelial growth factor (VEGF) and human umbilical vein endothelial cell (HUVEC)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos Cíclicos / Antígeno 96 de Linfócito / Receptor 4 Toll-Like / Neoplasias / Neovascularização Patológica Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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