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The Vietnamese pig as a translational animal model to evaluate tissue engineered heart valves: promising early experience.
Gallo, Michele; Poser, Helen; Bottio, Tommaso; Bonetti, Antonella; Franci, Paolo; Naso, Filippo; Buratto, Edward; Zanella, Fabio; Perona, Giovanni; Dal Lin, Carlo; Bianco, Roberto; Spina, Michele; Busetto, Roberto; Marchini, Maurizio; Ortolani, Fulvia; Iop, Laura; Gerosa, Gino.
Afiliação
  • Gallo M; Department of Cardiac, Thoracic and Vascular Science, University of Padua, Padua - Italy.
  • Poser H; Department of Animal Medicine, Production and Health, University of Padua, Padua - Italy.
  • Bottio T; Department of Cardiac, Thoracic and Vascular Science, University of Padua, Padua - Italy.
  • Bonetti A; Department of Experimental and Clinical Medicine, University of Udine, Udine - Italy.
  • Franci P; Department of Animal Medicine, Production and Health, University of Padua, Padua - Italy.
  • Naso F; Department of Cardiac, Thoracic and Vascular Science, University of Padua, Padua - Italy.
  • Buratto E; Department of Cardiothoracic Surgery, Royal Children's Hospital, Murdoch Children's Research Institute, University of Melbourne, Melbourne - Australia.
  • Zanella F; Department of Cardiac, Thoracic and Vascular Science, University of Padua, Padua - Italy.
  • Perona G; CISRA Institute, University of Turin, Turin - Italy.
  • Dal Lin C; Department of Cardiac, Thoracic and Vascular Science, University of Padua, Padua - Italy.
  • Bianco R; Department of Cardiac, Thoracic and Vascular Science, University of Padua, Padua - Italy.
  • Spina M; Department of Animal Medicine, Production and Health, University of Padua, Padua - Italy.
  • Busetto R; Department of Animal Medicine, Production and Health, University of Padua, Padua - Italy.
  • Marchini M; Department of Experimental and Clinical Medicine, University of Udine, Udine - Italy.
  • Ortolani F; Department of Experimental and Clinical Medicine, University of Udine, Udine - Italy.
  • Iop L; Department of Cardiac, Thoracic and Vascular Science, University of Padua, Padua - Italy.
  • Gerosa G; Cardiovascular Regenerative Medicine, Venetian Institute of Molecular Medicine (VIMM), Biomedical Campus Pietro d'Abano, Padua - Italy.
Int J Artif Organs ; 40(4): 142-149, 2017 May 09.
Article em En | MEDLINE | ID: mdl-28362047
ABSTRACT
Several animal models are currently used for the surgical implantation of either biologic or biopolymeric scaffolds in order to provide in vivo assessment of tissue-engineered heart valves. The Vietnamese pig (VP) is herein proposed as a suitable recipient to test the function of novel bioengineered valve substitutes, in the reconstruction of the right ventricular outflow tract (RVOT). This review aims to provide a complete and exhaustive panel of physiological parameters and methodological information for preclinical studies of tissue-engineered heart valves in the VP animal model.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Próteses Valvulares Cardíacas / Engenharia Tecidual Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Próteses Valvulares Cardíacas / Engenharia Tecidual Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article