Your browser doesn't support javascript.
loading
Usefulness of glycated hemoglobin A1c-based adjusted glycemic variables in diabetic patients presenting with acute ischemic stroke.
Yang, Chih-Jen; Liao, Wen-I; Wang, Jen-Chun; Tsai, Chia-Lin; Lee, Jiunn-Tay; Peng, Giia-Sheun; Lee, Chien-Hsing; Hsu, Chin-Wang; Tsai, Shih-Hung.
Afiliação
  • Yang CJ; Department of Emergency Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
  • Liao WI; Department of Emergency Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
  • Wang JC; Department of Emergency Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
  • Tsai CL; Department of Neurology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
  • Lee JT; Department of Neurology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
  • Peng GS; Department of Neurology, Taipei Veteran's General Hospital, Hsinchu Branch, Hsinchu, Taiwan.
  • Lee CH; Division of Endocrinology and Metabolism, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
  • Hsu CW; Department of Emergency Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taiwan; Department of Emergency and Critical Medicine, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.
  • Tsai SH; Department of Emergency Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan. Electronic address: tsaishihung@yahoo.com.tw.
Am J Emerg Med ; 35(9): 1240-1246, 2017 Sep.
Article em En | MEDLINE | ID: mdl-28363620
Acute hyperglycemia is a common condition among patients with diabetes who are admitted to the emergency department (ED) for acute ischemic stroke (AIS). Previous findings regarding the association between hyperglycemia at admission and adverse outcomes among patients with diabetes and AIS have been inconsistent. When investigating this association, it is necessary to consider premorbid blood glucose control. The objective of the current study was to assess whether HbA1c-based adjusted glycemic variables were associated with unfavorable outcomes among patients admitted to the hospital for AIS. We retrospectively analyzed data from 309 patients who were hospitalized for AIS at a single medical center in Taiwan between January 1, 2013, and October 31, 2015. We found that 1) HbA1c-based adjusted glycemic variables, including the glycemic gap and stress hyperglycemia ratio, were associated with both AIS severity and neurological status at discharge; additionally, 2) HbA1c-based adjusted glycemic variables showed superior discriminative power compared with acute hyperglycemia regarding the development of severe AIS. We conclude that both the glycemic gap and stress hyperglycemia ratio might be useful in assessing the disease severity and prognosis of patients presenting with AIS. Further prospective long-term follow-up studies should be performed to validate these findings.
Assuntos
Palavras-chave

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hemoglobinas Glicadas / Isquemia Encefálica / Mortalidade Hospitalar / Acidente Vascular Cerebral / Diabetes Mellitus / Hiperglicemia Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: Asia Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hemoglobinas Glicadas / Isquemia Encefálica / Mortalidade Hospitalar / Acidente Vascular Cerebral / Diabetes Mellitus / Hiperglicemia Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: Asia Idioma: En Ano de publicação: 2017 Tipo de documento: Article