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A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast cancer.
Betancur, Paola A; Abraham, Brian J; Yiu, Ying Y; Willingham, Stephen B; Khameneh, Farnaz; Zarnegar, Mark; Kuo, Angera H; McKenna, Kelly; Kojima, Yoko; Leeper, Nicholas J; Ho, Po; Gip, Phung; Swigut, Tomek; Sherwood, Richard I; Clarke, Michael F; Somlo, George; Young, Richard A; Weissman, Irving L.
Afiliação
  • Betancur PA; Institute for Stem Cell Biology and Regenerative Medicine, and Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Abraham BJ; Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA.
  • Yiu YY; Institute for Stem Cell Biology and Regenerative Medicine, and Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Willingham SB; Institute for Stem Cell Biology and Regenerative Medicine, and Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Khameneh F; Institute for Stem Cell Biology and Regenerative Medicine, and Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Zarnegar M; Institute for Stem Cell Biology and Regenerative Medicine, and Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Kuo AH; Institute for Stem Cell Biology and Regenerative Medicine, and Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
  • McKenna K; Institute for Stem Cell Biology and Regenerative Medicine, and Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Kojima Y; Department of Surgery, Division of Vascular Surgery, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Leeper NJ; Department of Surgery, Division of Vascular Surgery, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Ho P; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Gip P; Institute for Stem Cell Biology and Regenerative Medicine, and Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Swigut T; Institute for Stem Cell Biology and Regenerative Medicine, and Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Sherwood RI; Institute for Stem Cell Biology and Regenerative Medicine, and Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Clarke MF; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115 USA.
  • Somlo G; Institute for Stem Cell Biology and Regenerative Medicine, and Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
  • Young RA; Department of Medical Oncology &Therapeutics Research, City of Hope National Medical Center, Duarte, California 91010, USA.
  • Weissman IL; Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA.
Nat Commun ; 8: 14802, 2017 04 05.
Article em En | MEDLINE | ID: mdl-28378740

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Transdução de Sinais / Regulação para Cima / Elementos Facilitadores Genéticos / Mediadores da Inflamação / Antígeno CD47 / Inflamação Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Transdução de Sinais / Regulação para Cima / Elementos Facilitadores Genéticos / Mediadores da Inflamação / Antígeno CD47 / Inflamação Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article