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Understanding the Mechanism of the Broad-Spectrum Antiviral Activity of Favipiravir (T-705): Key Role of the F1 Motif of the Viral Polymerase.
Abdelnabi, Rana; Morais, Ana Theresa Silveira de; Leyssen, Pieter; Imbert, Isabelle; Beaucourt, Stéphanie; Blanc, Hervé; Froeyen, Mathy; Vignuzzi, Marco; Canard, Bruno; Neyts, Johan; Delang, Leen.
Afiliação
  • Abdelnabi R; KU Leuven-University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
  • Morais ATS; Architecture et Fonction des Macromolécules Biologiques, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 7257, Aix-Marseille Université, Marseille, France.
  • Leyssen P; KU Leuven-University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
  • Imbert I; Architecture et Fonction des Macromolécules Biologiques, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 7257, Aix-Marseille Université, Marseille, France.
  • Beaucourt S; Institut Pasteur, Centre National de la Recherche Scientifique UMR 3569, Paris, France.
  • Blanc H; Institut Pasteur, Centre National de la Recherche Scientifique UMR 3569, Paris, France.
  • Froeyen M; KU Leuven-University of Leuven, Department of Pharmaceutical and Pharmacological Sciences, Rega Institute for Medical Research, Laboratory of Medicinal Chemistry, Leuven, Belgium.
  • Vignuzzi M; Institut Pasteur, Centre National de la Recherche Scientifique UMR 3569, Paris, France.
  • Canard B; Architecture et Fonction des Macromolécules Biologiques, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 7257, Aix-Marseille Université, Marseille, France.
  • Neyts J; KU Leuven-University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium Johan.Neyts@kuleuven.be.
  • Delang L; KU Leuven-University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
J Virol ; 91(12)2017 06 15.
Article em En | MEDLINE | ID: mdl-28381577
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Pirazinas / RNA Polimerase Dependente de RNA / Enterovirus Humano B / Amidas / Lisina Limite: Animals País/Região como assunto: Asia Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Pirazinas / RNA Polimerase Dependente de RNA / Enterovirus Humano B / Amidas / Lisina Limite: Animals País/Região como assunto: Asia Idioma: En Ano de publicação: 2017 Tipo de documento: Article