Enantioselective total synthesis of (+)-arborescidine C and related tetracyclic indole alkaloids using organocatalysis.
Org Biomol Chem
; 15(16): 3408-3412, 2017 Apr 18.
Article
em En
| MEDLINE
| ID: mdl-28382347
ABSTRACT
A concise and enantioselective synthesis of the tetracyclic indoles, including the naturally occurring compounds (+)-arborescidine C and (+)-arborescidine B, was achieved by the key step of Pictet-Spengler cyclization reaction with a Jacobsen-type thiourea organocatalyst. The synthetic process was further demonstrated in a pot-economy strategy and was achieved in a one-pot operation.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Alcaloides Indólicos
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article