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Neurokinin 3 receptor antagonism as a novel treatment for menopausal hot flushes: a phase 2, randomised, double-blind, placebo-controlled trial.
Prague, Julia K; Roberts, Rachel E; Comninos, Alexander N; Clarke, Sophie; Jayasena, Channa N; Nash, Zachary; Doyle, Chedie; Papadopoulou, Deborah A; Bloom, Stephen R; Mohideen, Pharis; Panay, Nicholas; Hunter, Myra S; Veldhuis, Johannes D; Webber, Lorraine C; Huson, Les; Dhillo, Waljit S.
Afiliação
  • Prague JK; Department of Investigative Medicine, Imperial College London, London, UK.
  • Roberts RE; Department of Investigative Medicine, Imperial College London, London, UK.
  • Comninos AN; Department of Investigative Medicine, Imperial College London, London, UK.
  • Clarke S; Department of Investigative Medicine, Imperial College London, London, UK.
  • Jayasena CN; Department of Investigative Medicine, Imperial College London, London, UK.
  • Nash Z; Department of Investigative Medicine, Imperial College London, London, UK.
  • Doyle C; Department of Investigative Medicine, Imperial College London, London, UK.
  • Papadopoulou DA; Department of Investigative Medicine, Imperial College London, London, UK.
  • Bloom SR; Department of Investigative Medicine, Imperial College London, London, UK.
  • Mohideen P; Millendo Therapeutics, Inc, Ann Arbor, MI, USA.
  • Panay N; Department of Gynaecology, Queen Charlotte's & Chelsea Hospital and Chelsea and Westminster Hospital, London, UK; Institute of Reproductive and Developmental Biology, Imperial College London, London, UK.
  • Hunter MS; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
  • Veldhuis JD; Mayo Clinic, Rochester, MI, USA.
  • Webber LC; Scientific Partnering & Alliances, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Melbourn, UK.
  • Huson L; Division of Experimental Medicine, Imperial College London, London, UK.
  • Dhillo WS; Department of Investigative Medicine, Imperial College London, London, UK. Electronic address: w.dhillo@imperial.ac.uk.
Lancet ; 389(10081): 1809-1820, 2017 May 06.
Article em En | MEDLINE | ID: mdl-28385352

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Menopausa / Receptores da Neurocinina-3 / Fogachos Tipo de estudo: Clinical_trials / Etiology_studies / Guideline / Prognostic_studies Limite: Adult / Female / Humans / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Menopausa / Receptores da Neurocinina-3 / Fogachos Tipo de estudo: Clinical_trials / Etiology_studies / Guideline / Prognostic_studies Limite: Adult / Female / Humans / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article