Early assessment of tumor response to photodynamic therapy using combined diffuse optical and diffuse correlation spectroscopy to predict treatment outcome.

Thong, Patricia S P; Lee, Kijoon; Toh, Hui-Jin; Dong, Jing; Tee, Chuan-Sia; Low, Kar-Perng; Chang, Pui-Haan; Bhuvaneswari, Ramaswamy; Tan, Ngian-Chye; Soo, Khee-Chee

Thong, Patricia S P; Lee, Kijoon; Toh, Hui-Jin; Dong, Jing; Tee, Chuan-Sia; Low, Kar-Perng; Chang, Pui-Haan; Bhuvaneswari, Ramaswamy; Tan, Ngian-Chye; Soo, Khee-Chee.

Afiliação

Thong PSP; Division of Medical Sciences, National Cancer Centre, Singapore.
Lee K; Division of Bioengineering, School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore.
Toh HJ; Nanyang Technological University, Singapore.
Dong J; Current address: Daegu Gyeongbuk Institute of Science and Technology, Korea.
Tee CS; Division of Medical Sciences, National Cancer Centre, Singapore.
Low KP; Division of Bioengineering, School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore.
Chang PH; Nanyang Technological University, Singapore.
Bhuvaneswari R; Current address: Harvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, USA.
Tan NC; Division of Medical Sciences, National Cancer Centre, Singapore.
Soo KC; Division of Medical Sciences, National Cancer Centre, Singapore.

Oncotarget ; 8(12): 19902-19913, 2017 03 21.

Article em En | MEDLINE | ID: mdl-28423634

Assuntos

Neoplasias Mamárias Experimentais/tratamento farmacológico; Fotoquimioterapia/métodos; Fármacos Fotossensibilizantes/farmacologia; Análise Espectral/métodos; Animais; Linhagem Celular Tumoral; Endoscopia/métodos; Humanos; Luz; Neoplasias Mamárias Experimentais/irrigação sanguínea; Neoplasias Mamárias Experimentais/metabolismo; Camundongos Endogâmicos BALB C; Microscopia Confocal/métodos; Oxigênio/metabolismo; Prognóstico; Fluxo Sanguíneo Regional/efeitos dos fármacos; Análise de Sobrevida; Resultado do Tratamento; Carga Tumoral/efeitos dos fármacos

Palavras-chave

optical spectroscopy; photodynamic therapy; relative blood flow; tissue oxygenation; treatment response monitoring

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fotoquimioterapia / Análise Espectral / Fármacos Fotossensibilizantes / Neoplasias Mamárias Experimentais Tipo de estudo: Guideline / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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