Lactosylceramide-Induced Phosphorylation Signaling to Group IVA Phospholipase A<sub>2</sub> via Reactive Oxygen Species in Tumor Necrosis Factor-&#945;-Treated Cells.

Nakamura, Hiroyuki; Moriyama, Yuta; Watanabe, Kazuaki; Tomizawa, Satoshi; Yamazaki, Risa; Takahashi, Hiromasa; Murayama, Toshihiko

Lactosylceramide-Induced Phosphorylation Signaling to Group IVA Phospholipase A₂ via Reactive Oxygen Species in Tumor Necrosis Factor-α-Treated Cells.

Nakamura, Hiroyuki; Moriyama, Yuta; Watanabe, Kazuaki; Tomizawa, Satoshi; Yamazaki, Risa; Takahashi, Hiromasa; Murayama, Toshihiko.

Afiliação

Nakamura H; Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, 260-8675, Japan.
Moriyama Y; Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, 260-8675, Japan.
Watanabe K; Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, 260-8675, Japan.
Tomizawa S; Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, 260-8675, Japan.
Yamazaki R; Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, 260-8675, Japan.
Takahashi H; Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, 260-8675, Japan.
Murayama T; Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, 260-8675, Japan.

J Cell Biochem ; 118(12): 4370-4382, 2017 12.

Article em En | MEDLINE | ID: mdl-28444900

Assuntos

Antígenos CD/farmacologia; Fibroblastos/metabolismo; Fosfolipases A2 do Grupo IV/metabolismo; Lactosilceramidas/farmacologia; Sistema de Sinalização das MAP Quinases/efeitos dos fármacos; Espécies Reativas de Oxigênio/metabolismo; Fator de Necrose Tumoral alfa/farmacologia; Animais; Linhagem Celular; Camundongos; Fosforilação/efeitos dos fármacos

Palavras-chave

ERK1/2; LACTOSYLCERAMIDE; PROTEIN KINASE C; ROS; TNFα; cPLA2α

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antígenos CD / Fator de Necrose Tumoral alfa / Espécies Reativas de Oxigênio / Sistema de Sinalização das MAP Quinases / Fosfolipases A2 do Grupo IV / Fibroblastos / Lactosilceramidas Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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