Change in renin, cardiovascular and inflammatory markers over three years in a black and white population: the SABPA study.
BMC Cardiovasc Disord
; 17(1): 104, 2017 04 26.
Article
em En
| MEDLINE
| ID: mdl-28446166
ABSTRACT
BACKGROUND:
To investigate if percentage change (%∆) in renin over a 3 year follow-up is associated with %∆ in cardiovascular and inflammatory markers in a low renin bi-ethnic group.METHODS:
Blood pressure, active renin, C-reactive protein and interleukin-6 levels of 73 black and 81 white teachers were measured at baseline and after 3 years.RESULTS:
In the black group, %∆ renin was inversely associated with %∆ systolic blood pressure (ß = -0.27; p = 0.011). In the white group %∆ renin was inversely associated with %∆interleukin-6 (ß = -0.24; p = 0.005).CONCLUSIONS:
These prospective results indicate that a decrease in renin over time is associated with an increase in blood pressure in a low renin black South African cohort.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Interleucina-6
/
Renina
/
Mediadores da Inflamação
/
População Negra
/
População Branca
/
Hipertensão
/
Inflamação
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
Africa
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article