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Intrathecal Thyroid Autoantibody Synthesis in a Subgroup of Patients With Schizophreniform Syndromes.
Endres, Dominique; Dersch, Rick; Hochstuhl, Benedikt; Fiebich, Bernd; Hottenrott, Tilman; Perlov, Evgeniy; Maier, Simon; Berger, Benjamin; Baumgartner, Annette; Venhoff, Nils; Stich, Oliver; Tebartz van Elst, Ludger.
Afiliação
  • Endres D; From the Section for Experimental Neuropsychiatry, Department for Psychiatry & Psychotherapy, University Medical Center Freiburg, Freiburg, Germany (DE, BH, BF, EP, SM, LTvE); the Department for Neurology, University Medical Center Freiburg, Freiburg, Germany (RD, TH, BB, AB, OS); and the Depart
  • Dersch R; From the Section for Experimental Neuropsychiatry, Department for Psychiatry & Psychotherapy, University Medical Center Freiburg, Freiburg, Germany (DE, BH, BF, EP, SM, LTvE); the Department for Neurology, University Medical Center Freiburg, Freiburg, Germany (RD, TH, BB, AB, OS); and the Depart
  • Hochstuhl B; From the Section for Experimental Neuropsychiatry, Department for Psychiatry & Psychotherapy, University Medical Center Freiburg, Freiburg, Germany (DE, BH, BF, EP, SM, LTvE); the Department for Neurology, University Medical Center Freiburg, Freiburg, Germany (RD, TH, BB, AB, OS); and the Depart
  • Fiebich B; From the Section for Experimental Neuropsychiatry, Department for Psychiatry & Psychotherapy, University Medical Center Freiburg, Freiburg, Germany (DE, BH, BF, EP, SM, LTvE); the Department for Neurology, University Medical Center Freiburg, Freiburg, Germany (RD, TH, BB, AB, OS); and the Depart
  • Hottenrott T; From the Section for Experimental Neuropsychiatry, Department for Psychiatry & Psychotherapy, University Medical Center Freiburg, Freiburg, Germany (DE, BH, BF, EP, SM, LTvE); the Department for Neurology, University Medical Center Freiburg, Freiburg, Germany (RD, TH, BB, AB, OS); and the Depart
  • Perlov E; From the Section for Experimental Neuropsychiatry, Department for Psychiatry & Psychotherapy, University Medical Center Freiburg, Freiburg, Germany (DE, BH, BF, EP, SM, LTvE); the Department for Neurology, University Medical Center Freiburg, Freiburg, Germany (RD, TH, BB, AB, OS); and the Depart
  • Maier S; From the Section for Experimental Neuropsychiatry, Department for Psychiatry & Psychotherapy, University Medical Center Freiburg, Freiburg, Germany (DE, BH, BF, EP, SM, LTvE); the Department for Neurology, University Medical Center Freiburg, Freiburg, Germany (RD, TH, BB, AB, OS); and the Depart
  • Berger B; From the Section for Experimental Neuropsychiatry, Department for Psychiatry & Psychotherapy, University Medical Center Freiburg, Freiburg, Germany (DE, BH, BF, EP, SM, LTvE); the Department for Neurology, University Medical Center Freiburg, Freiburg, Germany (RD, TH, BB, AB, OS); and the Depart
  • Baumgartner A; From the Section for Experimental Neuropsychiatry, Department for Psychiatry & Psychotherapy, University Medical Center Freiburg, Freiburg, Germany (DE, BH, BF, EP, SM, LTvE); the Department for Neurology, University Medical Center Freiburg, Freiburg, Germany (RD, TH, BB, AB, OS); and the Depart
  • Venhoff N; From the Section for Experimental Neuropsychiatry, Department for Psychiatry & Psychotherapy, University Medical Center Freiburg, Freiburg, Germany (DE, BH, BF, EP, SM, LTvE); the Department for Neurology, University Medical Center Freiburg, Freiburg, Germany (RD, TH, BB, AB, OS); and the Depart
  • Stich O; From the Section for Experimental Neuropsychiatry, Department for Psychiatry & Psychotherapy, University Medical Center Freiburg, Freiburg, Germany (DE, BH, BF, EP, SM, LTvE); the Department for Neurology, University Medical Center Freiburg, Freiburg, Germany (RD, TH, BB, AB, OS); and the Depart
  • Tebartz van Elst L; From the Section for Experimental Neuropsychiatry, Department for Psychiatry & Psychotherapy, University Medical Center Freiburg, Freiburg, Germany (DE, BH, BF, EP, SM, LTvE); the Department for Neurology, University Medical Center Freiburg, Freiburg, Germany (RD, TH, BB, AB, OS); and the Depart
J Neuropsychiatry Clin Neurosci ; 29(4): 365-374, 2017.
Article em En | MEDLINE | ID: mdl-28449636
Schizophreniform syndromes in combination with autoimmune thyroiditis and increased serum thyroid antibodies lead healthcare practitioners to consider a diagnosis of Hashimoto's encephalopathy. To detect specific biomarkers, the authors analyzed whether intrathecal antithyroid antibody synthesis occurred in a subgroup of schizophreniform patients. In doing so, the authors analyzed thyroid antibodies in paired cerebrospinal fluid and serum samples from 100 schizophreniform patients. Increased antibody indices (AIs) for antithyroid peroxidase or antithyroglobulin autoantibodies in 13 schizophreniform patients were found. AIs were increased in 68% of the seropositive patients. These findings support the hypothesis that autoimmune processes may contribute to the pathophysiology in these patients.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtornos Psicóticos / Esquizofrenia / Autoanticorpos / Iodeto Peroxidase Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtornos Psicóticos / Esquizofrenia / Autoanticorpos / Iodeto Peroxidase Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article