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Thiolutin is a zinc chelator that inhibits the Rpn11 and other JAMM metalloproteases.
Lauinger, Linda; Li, Jing; Shostak, Anton; Cemel, Ibrahim Avi; Ha, Nati; Zhang, Yaru; Merkl, Philipp E; Obermeyer, Simon; Stankovic-Valentin, Nicolas; Schafmeier, Tobias; Wever, Walter J; Bowers, Albert A; Carter, Kyle P; Palmer, Amy E; Tschochner, Herbert; Melchior, Frauke; Deshaies, Raymond J; Brunner, Michael; Diernfellner, Axel.
Afiliação
  • Lauinger L; Heidelberg University Biochemistry Center, Heidelberg, Germany.
  • Li J; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California, USA.
  • Shostak A; Heidelberg University Biochemistry Center, Heidelberg, Germany.
  • Cemel IA; Heidelberg University Biochemistry Center, Heidelberg, Germany.
  • Ha N; Heidelberg University Biochemistry Center, Heidelberg, Germany.
  • Zhang Y; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California, USA.
  • Merkl PE; Lehrstuhl Biochemie III, Biochemie Zentrum Regensburg, Universität Regensburg, Regensburg, Germany.
  • Obermeyer S; Lehrstuhl Biochemie III, Biochemie Zentrum Regensburg, Universität Regensburg, Regensburg, Germany.
  • Stankovic-Valentin N; Zentrum Molekulare Biologie der Universität Heidelberg, DKFZ-ZMBH Alliance, Heidelberg University, Heidelberg, Germany.
  • Schafmeier T; Heidelberg University Biochemistry Center, Heidelberg, Germany.
  • Wever WJ; Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
  • Bowers AA; Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
  • Carter KP; Department of Chemistry and Biochemistry, BioFrontiers Institute, University of Colorado Boulder, Boulder, Colorado, USA.
  • Palmer AE; Department of Chemistry and Biochemistry, BioFrontiers Institute, University of Colorado Boulder, Boulder, Colorado, USA.
  • Tschochner H; Lehrstuhl Biochemie III, Biochemie Zentrum Regensburg, Universität Regensburg, Regensburg, Germany.
  • Melchior F; Zentrum Molekulare Biologie der Universität Heidelberg, DKFZ-ZMBH Alliance, Heidelberg University, Heidelberg, Germany.
  • Deshaies RJ; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California, USA.
  • Brunner M; Howard Hughes Medical Institute, California Institute of Technology, Pasadena, California, USA.
  • Diernfellner A; Heidelberg University Biochemistry Center, Heidelberg, Germany.
Nat Chem Biol ; 13(7): 709-714, 2017 Jul.
Article em En | MEDLINE | ID: mdl-28459440
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Zinco / Transativadores / Quelantes / Metaloproteases / Inibidores Enzimáticos Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Zinco / Transativadores / Quelantes / Metaloproteases / Inibidores Enzimáticos Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article