Genome-wide DNA methylation profiling reveals cancer-associated changes within early colonic neoplasia.

Hanley, M P; Hahn, M A; Li, A X; Wu, X; Lin, J; Wang, J; Choi, A H; Ouyang, Z; Fong, Y; Pfeifer, G P; Devers, T J; Rosenberg, D W

Hanley, M P; Hahn, M A; Li, A X; Wu, X; Lin, J; Wang, J; Choi, A H; Ouyang, Z; Fong, Y; Pfeifer, G P; Devers, T J; Rosenberg, D W.

Afiliação

Hanley MP; Center for Molecular Medicine, School of Medicine, UConn Health, Farmington, CT, USA.
Hahn MA; Department of Genetics and Genome Sciences, UConn Health, Farmington, CT, USA.
Li AX; Department of Surgery, City of Hope, Duarte, CA, USA.
Wu X; Department of Information Sciences, City of Hope, Duarte, CA, USA.
Lin J; Department of Molecular Medicine, Beckman Research Institute, City of Hope, Duarte, CA, USA.
Wang J; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Choi AH; Integrative Genomics Core, Beckman Research Institute, City of Hope, Duarte, CA, USA.
Ouyang Z; Department of Surgery, City of Hope, Duarte, CA, USA.
Fong Y; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Pfeifer GP; Institute for Systems Genomics, University of Connecticut, Farmington, CT, USA.
Devers TJ; Department of Surgery, City of Hope, Duarte, CA, USA.
Rosenberg DW; Center for Epigenetics, Van Andel Research Institute, Grand Rapids, MI, USA.

Oncogene ; 36(35): 5035-5044, 2017 08 31.

Article em En | MEDLINE | ID: mdl-28459462

Assuntos

Neoplasias do Colo/genética; Metilação de DNA; Lesões Pré-Cancerosas/genética; Biomarcadores Tumorais/genética; Biomarcadores Tumorais/metabolismo; Neoplasias do Colo/patologia; Estudo de Associação Genômica Ampla; Humanos; Microdissecção e Captura a Laser; Lesões Pré-Cancerosas/patologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lesões Pré-Cancerosas / Neoplasias do Colo / Metilação de DNA Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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