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The discovery of novel benzothiazinones as highly selective non-ATP competitive glycogen synthase kinase 3ß inhibitors for the treatment of ovarian cancer.
Gao, Yang; Ye, De-Yong; Zhou, Wei-Cheng; Chu, Yong.
Afiliação
  • Gao Y; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai, 201203, China; State Key Lab of New Drug & Pharmaceutical Process, Shanghai Key Lab of Anti-Infectives, State Institute of Pharmaceutical Industry, Shanghai, 201203, China.
  • Ye DY; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai, 201203, China. Electronic address: dyye@shmu.edu.cn.
  • Zhou WC; State Key Lab of New Drug & Pharmaceutical Process, Shanghai Key Lab of Anti-Infectives, State Institute of Pharmaceutical Industry, Shanghai, 201203, China. Electronic address: zhouweicheng58@163.com.
  • Chu Y; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai, 201203, China. Electronic address: cy110@fudan.edu.cn.
Eur J Med Chem ; 135: 370-381, 2017 Jul 28.
Article em En | MEDLINE | ID: mdl-28460311
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Inibidores de Proteínas Quinases / Benzotiazóis / Descoberta de Drogas / Glicogênio Sintase Quinase 3 beta Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Inibidores de Proteínas Quinases / Benzotiazóis / Descoberta de Drogas / Glicogênio Sintase Quinase 3 beta Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article