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Nuclear export of misfolded SOD1 mediated by a normally buried NES-like sequence reduces proteotoxicity in the nucleus.
Zhong, Yongwang; Wang, Jiou; Henderson, Mark J; Yang, Peixin; Hagen, Brian M; Siddique, Teepu; Vogel, Bruce E; Deng, Han-Xiang; Fang, Shengyun.
Afiliação
  • Zhong Y; Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, Baltimore, United States.
  • Wang J; Department of Physiology, University of Maryland School of Medicine, Baltimore, United States.
  • Henderson MJ; Department of Biochemistry and Molecular Biology, Johns Hopkins University, Baltimore, United States.
  • Yang P; Department of Neuroscience, Johns Hopkins University, Baltimore, United States.
  • Hagen BM; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, United States.
  • Siddique T; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, United States.
  • Vogel BE; Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, United States.
  • Deng HX; Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, Baltimore, United States.
  • Fang S; Department of Physiology, University of Maryland School of Medicine, Baltimore, United States.
Elife ; 62017 05 02.
Article em En | MEDLINE | ID: mdl-28463106
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dobramento de Proteína / Receptores Citoplasmáticos e Nucleares / Transporte Ativo do Núcleo Celular / Carioferinas / Superóxido Dismutase-1 Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dobramento de Proteína / Receptores Citoplasmáticos e Nucleares / Transporte Ativo do Núcleo Celular / Carioferinas / Superóxido Dismutase-1 Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article