Amitraz changes NE, DA and 5-HT biosynthesis and metabolism mediated by alterations in estradiol content in CNS of male rats.

Del Pino, Javier; Moyano, Paula; Ruiz, Matilde; Anadón, María José; Díaz, María Jesús; García, José Manuel; Labajo-González, Elena; Frejo, María Teresa

Del Pino, Javier; Moyano, Paula; Ruiz, Matilde; Anadón, María José; Díaz, María Jesús; García, José Manuel; Labajo-González, Elena; Frejo, María Teresa.

Afiliação

Del Pino J; Department of Toxicology and Pharmacology, Veterinary School, Complutense University of Madrid, 28040 Madrid, Spain. Electronic address: jdelpino@pdi.ucm.es.
Moyano P; Department of Toxicology and Legal Medicine, Medical School, Complutense University of Madrid, 28041 Madrid, Spain.
Ruiz M; Department of Toxicology and Legal Medicine, Medical School, Complutense University of Madrid, 28041 Madrid, Spain.
Anadón MJ; Department of Toxicology and Legal Medicine, Medical School, Complutense University of Madrid, 28041 Madrid, Spain.
Díaz MJ; Department of Toxicology and Pharmacology, Veterinary School, Complutense University of Madrid, 28040 Madrid, Spain.
García JM; Department of Toxicology and Legal Medicine, Medical School, Complutense University of Madrid, 28041 Madrid, Spain.
Labajo-González E; Department of Toxicology and Legal Medicine, Medical School, Complutense University of Madrid, 28041 Madrid, Spain.
Frejo MT; Department of Toxicology and Pharmacology, Veterinary School, Complutense University of Madrid, 28040 Madrid, Spain.

Chemosphere ; 181: 518-529, 2017 Aug.

Article em En | MEDLINE | ID: mdl-28463726

Assuntos

Sistema Nervoso Central/química; Dopamina/metabolismo; Estradiol/metabolismo; Inseticidas/toxicidade; Norepinefrina/metabolismo; Serotonina/metabolismo; Toluidinas/farmacologia; Animais; Encéfalo/efeitos dos fármacos; Encéfalo/enzimologia; Corpo Estriado/metabolismo; Dopamina/biossíntese; Estradiol/farmacologia; Regulação Enzimológica da Expressão Gênica/efeitos dos fármacos; Hipocampo/efeitos dos fármacos; Hipocampo/enzimologia; Inseticidas/farmacologia; Masculino; Neostriado/efeitos dos fármacos; Neostriado/enzimologia; Neurotransmissores/metabolismo; Norepinefrina/biossíntese; Córtex Pré-Frontal/efeitos dos fármacos; Córtex Pré-Frontal/enzimologia; Ratos; Serotonina/biossíntese; Tirosina 3-Mono-Oxigenase/metabolismo

Palavras-chave

Amitraz; Estradiol; Male rats; Monoaminergic neurotransmitters; Neurotoxicity

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Toluidinas / Dopamina / Serotonina / Norepinefrina / Sistema Nervoso Central / Estradiol / Inseticidas Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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