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NewProt - a protein engineering portal.
Schwarte, Andreas; Genz, Maika; Skalden, Lilly; Nobili, Alberto; Vickers, Clare; Melse, Okke; Kuipers, Remko; Joosten, Henk-Jan; Stourac, Jan; Bendl, Jaroslav; Black, Jon; Haase, Peter; Baakman, Coos; Damborsky, Jiri; Bornscheuer, Uwe; Vriend, Gert; Venselaar, Hanka.
Afiliação
  • Schwarte A; Fluid Operations AG, Walldorf, Germany.
  • Genz M; Department of Biotechnology and Enzyme Catalysis, Institute of Biochemistry, University of Greifswald, Felix-Hausdorff-Str. 4, 17487 Greifswald, Germany.
  • Skalden L; Department of Biotechnology and Enzyme Catalysis, Institute of Biochemistry, University of Greifswald, Felix-Hausdorff-Str. 4, 17487 Greifswald, Germany.
  • Nobili A; Department of Biotechnology and Enzyme Catalysis, Institute of Biochemistry, University of Greifswald, Felix-Hausdorff-Str. 4, 17487 Greifswald, Germany.
  • Vickers C; Department of Biotechnology and Enzyme Catalysis, Institute of Biochemistry, University of Greifswald, Felix-Hausdorff-Str. 4, 17487 Greifswald, Germany.
  • Melse O; Department of Biotechnology and Enzyme Catalysis, Institute of Biochemistry, University of Greifswald, Felix-Hausdorff-Str. 4, 17487 Greifswald, Germany.
  • Kuipers R; Bio-Prodict B.V., NieuweMarktstraat 54e, 6511 AA Nijmegen, The Netherlands.
  • Joosten HJ; Bio-Prodict B.V., NieuweMarktstraat 54e, 6511 AA Nijmegen, The Netherlands.
  • Stourac J; Enantis, INBIT, Kamenice 34, 625 00 Brno, Czech Republic.
  • Bendl J; Loschimidt Laboratories, Department of Experimental Biology and RECETOX, Faculty of Science, Masaryk University, Kamenice 5/A13, 625 00 BRNO, Czech Republic.
  • Black J; Enantis, INBIT, Kamenice 34, 625 00 Brno, Czech Republic.
  • Haase P; Loschimidt Laboratories, Department of Experimental Biology and RECETOX, Faculty of Science, Masaryk University, Kamenice 5/A13, 625 00 BRNO, Czech Republic.
  • Baakman C; CMBI, Radboud University Medical Centre, Geert Grooteplein Zuid 26-28, 6525 GA Nijmegen, The Netherlands.
  • Damborsky J; Fluid Operations AG, Altrottstraße 31, 69190 Walldorf, Germany.
  • Bornscheuer U; Metaphacts GmbH, Daimlerstraße 36, 69190 Walldorf, Germany.
  • Vriend G; CMBI, Radboud University Medical Centre, Geert Grooteplein Zuid 26-28, 6525 GA Nijmegen, The Netherlands.
  • Venselaar H; Enantis, INBIT, Kamenice 34, 625 00 Brno, Czech Republic.
Protein Eng Des Sel ; 30(6): 441-447, 2017 06 01.
Article em En | MEDLINE | ID: mdl-28475759
ABSTRACT
The NewProt protein engineering portal is a one-stop-shop for in silico protein engineering. It gives access to a large number of servers that compute a wide variety of protein structure characteristics supporting work on the modification of proteins through the introduction of (multiple) point mutations. The results can be inspected through multiple visualizers. The HOPE software is included to indicate mutations with possible undesired side effects. The Hotspot Wizard software is embedded for the design of mutations that modify a proteins' activity, specificity, or stability. The NewProt portal is freely accessible at http//newprot.cmbi.umcn.nl/ and http//newprot.fluidops.net/.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Software / Engenharia de Proteínas / Proteínas / Internet / Bases de Dados de Proteínas Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Software / Engenharia de Proteínas / Proteínas / Internet / Bases de Dados de Proteínas Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2017 Tipo de documento: Article