Retinopathy with central oedema in an INS <sup>C94Y</sup> transgenic pig model of long-term diabetes.

Kleinwort, Kristina J H; Amann, Barbara; Hauck, Stefanie M; Hirmer, Sieglinde; Blutke, Andreas; Renner, Simone; Uhl, Patrizia B; Lutterberg, Karina; Sekundo, Walter; Wolf, Eckhard; Deeg, Cornelia A

Retinopathy with central oedema in an INS ^C94Y transgenic pig model of long-term diabetes.

Kleinwort, Kristina J H; Amann, Barbara; Hauck, Stefanie M; Hirmer, Sieglinde; Blutke, Andreas; Renner, Simone; Uhl, Patrizia B; Lutterberg, Karina; Sekundo, Walter; Wolf, Eckhard; Deeg, Cornelia A.

Afiliação

Kleinwort KJH; Institute of Animal Physiology, Department of Veterinary Sciences, LMU Munich, Munich, Germany.
Amann B; Institute of Animal Physiology, Department of Veterinary Sciences, LMU Munich, Munich, Germany.
Hauck SM; Research Unit Protein Science, Helmholtz Zentrum München, German Research Centre for Environmental Health GmbH, Munich, Germany.
Hirmer S; German Centre for Diabetes Research (DZD), Neuherberg, Germany.
Blutke A; Institute of Animal Physiology, Department of Veterinary Sciences, LMU Munich, Munich, Germany.
Renner S; Institute of Veterinary Pathology, Centre for Clinical Veterinary Medicine, LMU Munich, Munich, Germany.
Uhl PB; German Centre for Diabetes Research (DZD), Neuherberg, Germany.
Lutterberg K; Molecular Animal Breeding and Biotechnology, Gene Centre, LMU Munich, Munich, Germany.
Sekundo W; Institute of Animal Physiology, Department of Veterinary Sciences, LMU Munich, Munich, Germany.
Wolf E; Institute of Animal Physiology, Department of Veterinary Sciences, LMU Munich, Munich, Germany.
Deeg CA; Department of Ophthalmology, Philipps University of Marburg, Marburg, Germany.

Diabetologia ; 60(8): 1541-1549, 2017 08.

Article em En | MEDLINE | ID: mdl-28480495

Assuntos

Retinopatia Diabética/genética; Hiperglicemia/genética; Insulina/metabolismo; Edema Macular/genética; Retina/patologia; Animais; Retinopatia Diabética/metabolismo; Retinopatia Diabética/patologia; Feminino; Humanos; Hiperglicemia/metabolismo; Hiperglicemia/patologia; Insulina/genética; Edema Macular/metabolismo; Edema Macular/patologia; Masculino; Camundongos Transgênicos; Pessoa de Meia-Idade; Retina/metabolismo; Suínos

Palavras-chave

Animal model; Cataract; Colour vision; Diabetes; Eye disease; Macular oedema; Pathophysiologic processes; Retinopathy; Vascular complications

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Retina / Edema Macular / Retinopatia Diabética / Hiperglicemia / Insulina Limite: Animals / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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