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Exploration of pyrrole derivatives to find an effective potassium-competitive acid blocker with moderately long-lasting suppression of gastric acid secretion.
Nishida, Haruyuki; Fujimori, Ikuo; Arikawa, Yasuyoshi; Hirase, Keizo; Ono, Koji; Nakai, Kazuo; Inatomi, Nobuhiro; Hori, Yasunobu; Matsukawa, Jun; Fujioka, Yasushi; Imanishi, Akio; Fukui, Hideo; Itoh, Fumio.
Afiliação
  • Nishida H; Pharmaceutical Research Division: Takeda Pharmaceutical Company, Ltd., 26-1, Muraokahigashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan. Electronic address: haruyuki.nishida@takeda.com.
  • Fujimori I; Pharmaceutical Research Division: Takeda Pharmaceutical Company, Ltd., 26-1, Muraokahigashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Arikawa Y; Pharmaceutical Research Division: Takeda Pharmaceutical Company, Ltd., 26-1, Muraokahigashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Hirase K; Pharmaceutical Research Division: Takeda Pharmaceutical Company, Ltd., 26-1, Muraokahigashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Ono K; Pharmaceutical Research Division: Takeda Pharmaceutical Company, Ltd., 26-1, Muraokahigashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Nakai K; Pharmaceutical Research Division: Takeda Pharmaceutical Company, Ltd., 26-1, Muraokahigashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Inatomi N; Pharmaceutical Research Division: Takeda Pharmaceutical Company, Ltd., 26-1, Muraokahigashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Hori Y; Pharmaceutical Research Division: Takeda Pharmaceutical Company, Ltd., 26-1, Muraokahigashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Matsukawa J; Pharmaceutical Research Division: Takeda Pharmaceutical Company, Ltd., 26-1, Muraokahigashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Fujioka Y; Pharmaceutical Research Division: Takeda Pharmaceutical Company, Ltd., 26-1, Muraokahigashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Imanishi A; Pharmaceutical Research Division: Takeda Pharmaceutical Company, Ltd., 26-1, Muraokahigashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Fukui H; Pharmaceutical Research Division: Takeda Pharmaceutical Company, Ltd., 26-1, Muraokahigashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
  • Itoh F; Pharmaceutical Research Division: Takeda Pharmaceutical Company, Ltd., 26-1, Muraokahigashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.
Bioorg Med Chem ; 25(13): 3447-3460, 2017 07 01.
Article em En | MEDLINE | ID: mdl-28483454
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Potássio / Pirróis / ATPase Trocadora de Hidrogênio-Potássio / Inibidores da Bomba de Prótons / Ácido Gástrico Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Potássio / Pirróis / ATPase Trocadora de Hidrogênio-Potássio / Inibidores da Bomba de Prótons / Ácido Gástrico Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2017 Tipo de documento: Article