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Hypoxia treatment reverses neurodegenerative disease in a mouse model of Leigh syndrome.
Ferrari, Michele; Jain, Isha H; Goldberger, Olga; Rezoagli, Emanuele; Thoonen, Robrecht; Cheng, Kai-Hung; Sosnovik, David E; Scherrer-Crosbie, Marielle; Mootha, Vamsi K; Zapol, Warren M.
Afiliação
  • Ferrari M; Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston, MA 02114.
  • Jain IH; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114.
  • Goldberger O; Howard Hughes Medical Institute, Massachusetts General Hospital, Boston, MA 02114.
  • Rezoagli E; Department of Systems Biology, Harvard Medical School, Boston, MA 02114.
  • Thoonen R; Broad Institute of Harvard and MIT, Cambridge, MA 02142.
  • Cheng KH; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114.
  • Sosnovik DE; Howard Hughes Medical Institute, Massachusetts General Hospital, Boston, MA 02114.
  • Scherrer-Crosbie M; Department of Systems Biology, Harvard Medical School, Boston, MA 02114.
  • Mootha VK; Broad Institute of Harvard and MIT, Cambridge, MA 02142.
  • Zapol WM; Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston, MA 02114.
Proc Natl Acad Sci U S A ; 114(21): E4241-E4250, 2017 05 23.
Article em En | MEDLINE | ID: mdl-28483998

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Leigh / Doenças Neurodegenerativas / Complexo I de Transporte de Elétrons / Hipóxia / Mitocôndrias Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Leigh / Doenças Neurodegenerativas / Complexo I de Transporte de Elétrons / Hipóxia / Mitocôndrias Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article