Presence of inflammatory proteins S100A8 and S100A9 in a giant intracranial aneurysm after flow diverter treatment.

de Korte, Antonius M; Aquarius, René; Meijer, Frederick J A; van Lent, Peter; Boogaarts, Hieronymus D; de Vries, Joost

de Korte, Antonius M; Aquarius, René; Meijer, Frederick J A; van Lent, Peter; Boogaarts, Hieronymus D; de Vries, Joost.

Afiliação

de Korte AM; a Department of Neurosurgery , Radboud University Medical Center , Nijmegen , The Netherlands.
Aquarius R; a Department of Neurosurgery , Radboud University Medical Center , Nijmegen , The Netherlands.
Meijer FJA; b Department of Pathology , Radboud University Medical Center , Nijmegen , The Netherlands.
van Lent P; c Department of Radiology , Radboud University Medical Center , Nijmegen , The Netherlands.
Boogaarts HD; d Department of Rheumatology , Radboud University Medical Center , Nijmegen , The Netherlands.
de Vries J; a Department of Neurosurgery , Radboud University Medical Center , Nijmegen , The Netherlands.

Br J Neurosurg ; 33(3): 258-260, 2019 Jun.

Article em En | MEDLINE | ID: mdl-28494622

ABSTRACT

ABSTRACT

We demonstrate the presence of S100A8 and S100A9 proteins in the wall and thrombosed lumen of an enlarged intracranial aneurysm after flow diverter treatment. These proteins have shown to play an important role in vascular inflammation and may serve as a biomarker and potential therapeutic target for intracranial aneurysms.

Assuntos

Calgranulina A/metabolismo; Calgranulina B/metabolismo; Aneurisma Intracraniano/metabolismo; Aneurisma Intracraniano/cirurgia; Angiografia Digital; Prótese Vascular; Implante de Prótese Vascular; Calgranulina A/análise; Calgranulina B/análise; Embolização Terapêutica; Procedimentos Endovasculares; Feminino; Humanos; Imuno-Histoquímica; Aneurisma Intracraniano/diagnóstico por imagem; Pessoa de Meia-Idade; Procedimentos Neurocirúrgicos; Resultado do Tratamento; Transtornos da Visão/etiologia

Palavras-chave

Intracranial aneurysm; S100A8; S100A9; aneurysm enlargement; flow diverter

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Aneurisma Intracraniano / Calgranulina A / Calgranulina B Tipo de estudo: Etiology_studies Limite: Female / Humans / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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