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USP7 inhibition alters homologous recombination repair and targets CLL cells independently of ATM/p53 functional status.
Agathanggelou, Angelo; Smith, Edward; Davies, Nicholas J; Kwok, Marwan; Zlatanou, Anastasia; Oldreive, Ceri E; Mao, Jingwen; Da Costa, David; Yadollahi, Sina; Perry, Tracey; Kearns, Pamela; Skowronska, Anna; Yates, Elliot; Parry, Helen; Hillmen, Peter; Reverdy, Celine; Delansorne, Remi; Paneesha, Shankara; Pratt, Guy; Moss, Paul; Taylor, A Malcolm R; Stewart, Grant S; Stankovic, Tatjana.
Afiliação
  • Agathanggelou A; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
  • Smith E; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
  • Davies NJ; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
  • Kwok M; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
  • Zlatanou A; Centre for Clinical Haematology, Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom.
  • Oldreive CE; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
  • Mao J; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
  • Da Costa D; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
  • Yadollahi S; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
  • Perry T; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
  • Kearns P; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
  • Skowronska A; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
  • Yates E; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
  • Parry H; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
  • Hillmen P; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
  • Reverdy C; Centre for Clinical Haematology, Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom.
  • Delansorne R; Section of Experimental Haematology, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, United Kingdom.
  • Paneesha S; Hybrigenics Services, Paris, France; and.
  • Pratt G; Hybrigenics Services, Paris, France; and.
  • Moss P; Heartlands Hospital, Birmingham, United Kingdom.
  • Taylor AMR; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
  • Stewart GS; Centre for Clinical Haematology, Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom.
  • Stankovic T; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
Blood ; 130(2): 156-166, 2017 07 13.
Article em En | MEDLINE | ID: mdl-28495793
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Linfocítica Crônica de Células B / Regulação Neoplásica da Expressão Gênica / Proteína Supressora de Tumor p53 / Reparo de DNA por Recombinação / Proteases Específicas de Ubiquitina Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Linfocítica Crônica de Células B / Regulação Neoplásica da Expressão Gênica / Proteína Supressora de Tumor p53 / Reparo de DNA por Recombinação / Proteases Específicas de Ubiquitina Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article