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Selective BET bromodomain inhibition as an antifungal therapeutic strategy.
Mietton, Flore; Ferri, Elena; Champleboux, Morgane; Zala, Ninon; Maubon, Danièle; Zhou, Yingsheng; Harbut, Mike; Spittler, Didier; Garnaud, Cécile; Courçon, Marie; Chauvel, Murielle; d'Enfert, Christophe; Kashemirov, Boris A; Hull, Mitchell; Cornet, Muriel; McKenna, Charles E; Govin, Jérôme; Petosa, Carlo.
Afiliação
  • Mietton F; Institut de Biosciences et Biotechnologies de Grenoble, Laboratoire Biologie à Grande Échelle, Université de Grenoble Alpes, CEA, Inserm, 38000 Grenoble, France.
  • Ferri E; Institut de Biologie Structurale (IBS), Université de Grenoble Alpes, CEA, CNRS, 38044 Grenoble, France.
  • Champleboux M; Department of Chemistry, Dana and David Dornsife College of Letters, Arts and Sciences, University of Southern California, University Park Campus, Los Angeles, California 90089, USA.
  • Zala N; Institut de Biosciences et Biotechnologies de Grenoble, Laboratoire Biologie à Grande Échelle, Université de Grenoble Alpes, CEA, Inserm, 38000 Grenoble, France.
  • Maubon D; Institut de Biosciences et Biotechnologies de Grenoble, Laboratoire Biologie à Grande Échelle, Université de Grenoble Alpes, CEA, Inserm, 38000 Grenoble, France.
  • Zhou Y; Laboratoire de Parasitologie-Mycologie, Institut de Biologie et Pathologie, CHU Grenoble Alpes, 38043 Grenoble, France.
  • Harbut M; Laboratoire TIMC-IMAG-TheREx, UMR 5525 CNRS, Université Grenoble Alpes, 38058 Grenoble, France.
  • Spittler D; Department of Chemistry, Dana and David Dornsife College of Letters, Arts and Sciences, University of Southern California, University Park Campus, Los Angeles, California 90089, USA.
  • Garnaud C; California Institute for Biomedical Research, 11119 N Torrey Pines Rd, La Jolla, California 92037, USA.
  • Courçon M; Institut de Biologie Structurale (IBS), Université de Grenoble Alpes, CEA, CNRS, 38044 Grenoble, France.
  • Chauvel M; Laboratoire de Parasitologie-Mycologie, Institut de Biologie et Pathologie, CHU Grenoble Alpes, 38043 Grenoble, France.
  • d'Enfert C; Laboratoire TIMC-IMAG-TheREx, UMR 5525 CNRS, Université Grenoble Alpes, 38058 Grenoble, France.
  • Kashemirov BA; Institut de Biosciences et Biotechnologies de Grenoble, Laboratoire Biologie à Grande Échelle, Université de Grenoble Alpes, CEA, Inserm, 38000 Grenoble, France.
  • Hull M; Unité Biologie et Pathogénicité Fongiques, Institut Pasteur, INRA, 75015 Paris, France.
  • Cornet M; Unité Biologie et Pathogénicité Fongiques, Institut Pasteur, INRA, 75015 Paris, France.
  • McKenna CE; Department of Chemistry, Dana and David Dornsife College of Letters, Arts and Sciences, University of Southern California, University Park Campus, Los Angeles, California 90089, USA.
  • Govin J; California Institute for Biomedical Research, 11119 N Torrey Pines Rd, La Jolla, California 92037, USA.
  • Petosa C; Laboratoire de Parasitologie-Mycologie, Institut de Biologie et Pathologie, CHU Grenoble Alpes, 38043 Grenoble, France.
Nat Commun ; 8: 15482, 2017 05 18.
Article em En | MEDLINE | ID: mdl-28516956
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Candida albicans / Candidíase / Proteínas Fúngicas / Terapia de Alvo Molecular / Antifúngicos Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Candida albicans / Candidíase / Proteínas Fúngicas / Terapia de Alvo Molecular / Antifúngicos Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2017 Tipo de documento: Article