Increased chemo-sensitivity by knockdown coilin expression involved acceleration of premature cellular senescence in HeLa cells.

Song, Yaoyao; Niu, Jing; Yue, Zhixia; Gao, Ruiqi; Zhang, Chenguang; Ding, Wei

Song, Yaoyao; Niu, Jing; Yue, Zhixia; Gao, Ruiqi; Zhang, Chenguang; Ding, Wei.

Afiliação

Song Y; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Capital Medical University, PR China.
Niu J; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Capital Medical University, PR China; Beijing Key Laboratory for Tumor Invasion and Metastasis Research, Cancer Institute of Capital Medical University, PR China.
Yue Z; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Capital Medical University, PR China; Hematology Oncology Center at Beijing Children's Hospital in Affiliation of Capital Medical University, PR China.
Gao R; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Capital Medical University, PR China.
Zhang C; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Capital Medical University, PR China; Beijing Key Laboratory for Tumor Invasion and Metastasis Research, Cancer Institute of Capital Medical University, PR China.
Ding W; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Capital Medical University, PR China; Beijing Key Laboratory for Tumor Invasion and Metastasis Research, Cancer Institute of Capital Medical University, PR China; Beijing Institute of Brain Disorders, PR China. Elect

Biochem Biophys Res Commun ; 489(2): 123-129, 2017 07 22.

Article em En | MEDLINE | ID: mdl-28536075

Assuntos

Antineoplásicos/farmacologia; Senescência Celular/efeitos dos fármacos; Cisplatino/farmacologia; Proteínas Nucleares/biossíntese; Antineoplásicos/química; Biomarcadores Tumorais/biossíntese; Biomarcadores Tumorais/genética; Biomarcadores Tumorais/metabolismo; Proliferação de Células/efeitos dos fármacos; Cisplatino/química; Relação Dose-Resposta a Droga; Ensaios de Seleção de Medicamentos Antitumorais; Células HeLa; Humanos; Proteínas Nucleares/genética; Proteínas Nucleares/metabolismo; Relação Estrutura-Atividade; Células Tumorais Cultivadas

Palavras-chave

Cajal body; Cisplatin; Coilin; SA-ß-gal; Senescence

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Nucleares / Cisplatino / Senescência Celular / Antineoplásicos Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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