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Splicing factor SF3B1K700E mutant dysregulates erythroid differentiation via aberrant alternative splicing of transcription factor TAL1.
Jin, Shuiling; Su, Hairui; Tran, Ngoc-Tung; Song, Jing; Lu, Sydney S; Li, Ying; Huang, Suming; Abdel-Wahab, Omar; Liu, Yanyan; Zhao, Xinyang.
Afiliação
  • Jin S; Department of Internal Medicine, Henan Cancer Hospital & Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, China.
  • Su H; Department of Biochemistry and Molecular Genetics, The University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
  • Tran NT; Department of Biochemistry and Molecular Genetics, The University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
  • Song J; Department of Biochemistry and Molecular Genetics, The University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
  • Lu SS; Department of Internal Medicine, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
  • Li Y; Human Oncology & Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America.
  • Huang S; Macau Institute for Applied Research in Medicine and Health, State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, Macau. China.
  • Abdel-Wahab O; Department of Biochemistry and Molecular Biology, College of Medicine, University of Florida, Gainesville, Florida, United States of America.
  • Liu Y; Human Oncology & Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America.
  • Zhao X; Department of Internal Medicine, Henan Cancer Hospital & Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, China.
PLoS One ; 12(5): e0175523, 2017.
Article em En | MEDLINE | ID: mdl-28545085
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Diferenciação Celular / Proteínas Proto-Oncogênicas / Processamento Alternativo / Células Eritroides / Fatores de Transcrição Hélice-Alça-Hélice Básicos / Fatores de Processamento de RNA / Mutação Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Diferenciação Celular / Proteínas Proto-Oncogênicas / Processamento Alternativo / Células Eritroides / Fatores de Transcrição Hélice-Alça-Hélice Básicos / Fatores de Processamento de RNA / Mutação Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article