Successful Treatment of BK Virus Hemorrhagic Cystitis (HC) Post Allogenic Hematopoietic Stem Cell Transplantation with Low Dose Cidofovir.
J Assoc Physicians India
; 65(5): 93-94, 2017 May.
Article
em En
| MEDLINE
| ID: mdl-28598058
ABSTRACT
BK virus (BKV) hemorrhagic cystitis (HC) is a serious cause of morbidity and mortality after allogeneic hematopoietic SCT (allo-HSCT) in patients with hematological malignancies. Around half of allogenic HSCT patients present with BKV viruria at some point after HSCT; about 5-40% of these patients subsequently develop active HC. Supportive care including bladder irrigation, blood transfusions and symptomatic pain management remains the mainstay of therapy; the acyclic nucleoside analogue cidofovir is currently the front-line drug for BKV-HC treatment. Here we report the first case of severe hemorrhagic cystitis from India who was successfully treated with low dose cidofovir therapy.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Antivirais
/
Infecções Tumorais por Vírus
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Cistite
/
Infecções por Polyomavirus
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Citosina
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Organofosfonatos
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Hemorragia
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article