Nanostructures Integrated with a Nanochannel for Slowing Down DNA Translocation Velocity for Nanopore Sequencing.
Anal Sci
; 33(6): 735-738, 2017.
Article
em En
| MEDLINE
| ID: mdl-28603196
ABSTRACT
Here, we developed a device integrated with a nanochannel and nanostructures to slow DNA translocation velocity. We found that translocation velocity of a single DNA molecule inside a nanochannel was decreased by pre-elongating it using some nanostructures, such as a shallow channel or nanopillars. This decrease of the translocation velocity was associated with the DNA mobility change, which is an intrinsic parameter of DNA molecules and unaffected by an electric field.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
DNA de Cadeia Simples
/
Nanotecnologia
/
Nanoestruturas
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article