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Cellular senescence drives age-dependent hepatic steatosis.
Ogrodnik, Mikolaj; Miwa, Satomi; Tchkonia, Tamar; Tiniakos, Dina; Wilson, Caroline L; Lahat, Albert; Day, Christoper P; Burt, Alastair; Palmer, Allyson; Anstee, Quentin M; Grellscheid, Sushma Nagaraja; Hoeijmakers, Jan H J; Barnhoorn, Sander; Mann, Derek A; Bird, Thomas G; Vermeij, Wilbert P; Kirkland, James L; Passos, João F; von Zglinicki, Thomas; Jurk, Diana.
Afiliação
  • Ogrodnik M; Newcastle University Institute for Ageing, Institute for Cell and Molecular Biosciences, Campus for Ageing and Vitality, Newcastle University, Newcastle upon Tyne NE4 5PL, UK.
  • Miwa S; Newcastle University Institute for Ageing, Institute for Cell and Molecular Biosciences, Campus for Ageing and Vitality, Newcastle University, Newcastle upon Tyne NE4 5PL, UK.
  • Tchkonia T; Robert and Arlene Kogod Center on Aging, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA.
  • Tiniakos D; Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
  • Wilson CL; Department of Pathology, Aretaieio Hospital, Medical School, National &Kapodistrian University of Athens, Athens 11528, Greece.
  • Lahat A; Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
  • Day CP; Department of Biosciences, Durham University, Durham DH1 3LE, UK.
  • Burt A; Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
  • Palmer A; Liver Unit, Newcastle upon Tyne Hospitals NHS Trust, Freeman Hospital, Newcastle upon Tyne NE7 7DN, UK.
  • Anstee QM; Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
  • Grellscheid SN; The University of Adelaide, Faculty of Health Science, North Terrace, Adelaide, South Australia 5005, Australia.
  • Hoeijmakers JHJ; Robert and Arlene Kogod Center on Aging, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA.
  • Barnhoorn S; Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
  • Mann DA; Department of Biosciences, Durham University, Durham DH1 3LE, UK.
  • Bird TG; Department of Molecular Genetics, Erasmus University Medical Center, PO Box 2040, Rotterdam 3000 CA, The Netherlands.
  • Vermeij WP; CECAD Forschungszentrum, Universität zu Köln, Joseph-Stelzmann-Straße 26, Köln 50931, Germany.
  • Kirkland JL; Department of Molecular Genetics, Erasmus University Medical Center, PO Box 2040, Rotterdam 3000 CA, The Netherlands.
  • Passos JF; Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
  • von Zglinicki T; MRC Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK.
  • Jurk D; Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK.
Nat Commun ; 8: 15691, 2017 06 13.
Article em En | MEDLINE | ID: mdl-28608850
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quercetina / Senescência Celular / Fígado Gorduroso / Dasatinibe / Inflamação Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quercetina / Senescência Celular / Fígado Gorduroso / Dasatinibe / Inflamação Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article