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Gastrointestinal and Systemic Disposition of Diclofenac under Fasted and Fed State Conditions Supporting the Evaluation of in Vitro Predictive Tools.
Van Den Abeele, Jens; Schilderink, Ronald; Schneider, Felix; Mols, Raf; Minekus, Mans; Weitschies, Werner; Brouwers, Joachim; Tack, Jan; Augustijns, Patrick.
Afiliação
  • Van Den Abeele J; Drug Delivery and Disposition, KU Leuven , Gasthuisberg O&N II, Herestraat 49, Box 921, 3000 Leuven, Belgium.
  • Schilderink R; TNO , P.O. 360, 3700 AJ, Zeist, The Netherlands.
  • Schneider F; Triskelion B.V. , P.O. Box 844, 3700 AV Zeist, The Netherlands.
  • Mols R; Department of Biopharmaceutics and Pharmaceutical Technology, Center of Drug Absorption and Transport, University of Greifswald , Felix-Hausdorff-Straße 3, 17489 Greifswald, Germany.
  • Minekus M; Drug Delivery and Disposition, KU Leuven , Gasthuisberg O&N II, Herestraat 49, Box 921, 3000 Leuven, Belgium.
  • Weitschies W; TNO , P.O. 360, 3700 AJ, Zeist, The Netherlands.
  • Brouwers J; Triskelion B.V. , P.O. Box 844, 3700 AV Zeist, The Netherlands.
  • Tack J; Department of Biopharmaceutics and Pharmaceutical Technology, Center of Drug Absorption and Transport, University of Greifswald , Felix-Hausdorff-Straße 3, 17489 Greifswald, Germany.
  • Augustijns P; Drug Delivery and Disposition, KU Leuven , Gasthuisberg O&N II, Herestraat 49, Box 921, 3000 Leuven, Belgium.
Mol Pharm ; 14(12): 4220-4232, 2017 12 04.
Article em En | MEDLINE | ID: mdl-28621952
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Técnicas In Vitro / Diclofenaco / Liberação Controlada de Fármacos / Absorção Intestinal Tipo de estudo: Evaluation_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Técnicas In Vitro / Diclofenaco / Liberação Controlada de Fármacos / Absorção Intestinal Tipo de estudo: Evaluation_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male Idioma: En Ano de publicação: 2017 Tipo de documento: Article