CRISPR/Cas9-Mediated Genome Editing Corrects Dystrophin Mutation in Skeletal Muscle Stem Cells in a Mouse Model of Muscle Dystrophy.

Zhu, Pei; Wu, Furen; Mosenson, Jeffrey; Zhang, Hongmei; He, Tong-Chuan; Wu, Wen-Shu

Zhu, Pei; Wu, Furen; Mosenson, Jeffrey; Zhang, Hongmei; He, Tong-Chuan; Wu, Wen-Shu.

Afiliação

Zhu P; Division of Hematology/Oncology, Department of Medicine and Cancer Center, University of Illinois at Chicago, Chicago, IL 60612, USA.
Wu F; Division of Hematology/Oncology, Department of Medicine and Cancer Center, University of Illinois at Chicago, Chicago, IL 60612, USA.
Mosenson J; Division of Hematology/Oncology, Department of Medicine and Cancer Center, University of Illinois at Chicago, Chicago, IL 60612, USA.
Zhang H; Department of Orthopaedic Surgery and Rehabilitation Medicine, The University of Chicago Medical Center, Chicago, IL 60637, USA.
He TC; Department of Orthopaedic Surgery and Rehabilitation Medicine, The University of Chicago Medical Center, Chicago, IL 60637, USA.
Wu WS; Division of Hematology/Oncology, Department of Medicine and Cancer Center, University of Illinois at Chicago, Chicago, IL 60612, USA. Electronic address: wuwenshu@uic.edu.

Mol Ther Nucleic Acids ; 7: 31-41, 2017 Jun 16.

Article em En | MEDLINE | ID: mdl-28624206

Palavras-chave

3D fibrin gel; CRISPR/Cas9; DMD; Duchenne muscular dystrophy; ex vivo expansion; genome editing; muscle stem cells

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article