Genes encoding cuticular proteins are components of the Nimrod gene cluster in Drosophila.
Insect Biochem Mol Biol
; 87: 45-54, 2017 08.
Article
em En
| MEDLINE
| ID: mdl-28633893
ABSTRACT
The Nimrod gene cluster, located on the second chromosome of Drosophila melanogaster, is the largest synthenic unit of the Drosophila genome. Nimrod genes show blood cell specific expression and code for phagocytosis receptors that play a major role in fruit fly innate immune functions. We previously identified three homologous genes (vajk-1, vajk-2 and vajk-3) located within the Nimrod cluster, which are unrelated to the Nimrod genes, but are homologous to a fourth gene (vajk-4) located outside the cluster. Here we show that, unlike the Nimrod candidates, the Vajk proteins are expressed in cuticular structures of the late embryo and the late pupa, indicating that they contribute to cuticular barrier functions.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Família Multigênica
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Genes de Insetos
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Proteínas de Drosophila
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Drosophila melanogaster
Limite:
Animals
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article