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Reactive sulfur species inactivate Ca2+/calmodulin-dependent protein kinase IV via S-polysulfidation of its active-site cysteine residue.
Takata, Tsuyoshi; Ihara, Hideshi; Hatano, Naoya; Tsuchiya, Yukihiro; Akaike, Takaaki; Watanabe, Yasuo.
Afiliação
  • Takata T; Department of Pharmacology, High Technology Research Center, Showa Pharmaceutical University, Machida, Tokyo 194-8543, Japan.
  • Ihara H; Department of Biological Science, Graduate School of Science, Osaka Prefecture University, Sakai, Osaka 599-8531, Japan.
  • Hatano N; The Integrated Center for Mass Spectrometry, Graduate School of Medicine, Kobe University, Kobe 650-0017, Japan.
  • Tsuchiya Y; Department of Pharmacology, High Technology Research Center, Showa Pharmaceutical University, Machida, Tokyo 194-8543, Japan.
  • Akaike T; Department of Environmental Health Sciences and Molecular Toxicology, Graduate School of Medicine, Tohoku University, Miyagi 980-8575, Japan.
  • Watanabe Y; Department of Pharmacology, High Technology Research Center, Showa Pharmaceutical University, Machida, Tokyo 194-8543, Japan yasuwata@ac.shoyaku.ac.jp.
Biochem J ; 474(15): 2547-2562, 2017 07 17.
Article em En | MEDLINE | ID: mdl-28637792
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfetos / Enxofre / Cisteína / Proteína Quinase Tipo 4 Dependente de Cálcio-Calmodulina Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfetos / Enxofre / Cisteína / Proteína Quinase Tipo 4 Dependente de Cálcio-Calmodulina Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article