Hypoxia-Induced Changes in the Fibroblast Secretome, Exosome, and Whole-Cell Proteome Using Cultured, Cardiac-Derived Cells Isolated from Neonatal Mice.

Cosme, Jake; Guo, Hongbo; Hadipour-Lakmehsari, Sina; Emili, Andrew; Gramolini, Anthony O

Cosme, Jake; Guo, Hongbo; Hadipour-Lakmehsari, Sina; Emili, Andrew; Gramolini, Anthony O.

Afiliação

Cosme J; Department of Physiology and Translational Biology and Engineering Program (TBEP), University of Toronto , Toronto, Ontario M5G 1M1, Canada.
Guo H; The Donnelly Centre for Cellular and Biomolecular Research, Ted Rogers Centre for Heart Research, University of Toronto , Toronto, Ontario M5S 3E1, Canada.
Hadipour-Lakmehsari S; Department of Physiology and Translational Biology and Engineering Program (TBEP), University of Toronto , Toronto, Ontario M5G 1M1, Canada.
Emili A; The Donnelly Centre for Cellular and Biomolecular Research, Ted Rogers Centre for Heart Research, University of Toronto , Toronto, Ontario M5S 3E1, Canada.
Gramolini AO; Department of Physiology and Translational Biology and Engineering Program (TBEP), University of Toronto , Toronto, Ontario M5G 1M1, Canada.

J Proteome Res ; 16(8): 2836-2847, 2017 08 04.

Article em En | MEDLINE | ID: mdl-28641008

Assuntos

Fibroblastos/metabolismo; Hipóxia/patologia; Miocárdio/citologia; Animais; Animais Recém-Nascidos; Células Cultivadas; Exossomos/metabolismo; Fibroblastos/patologia; Camundongos; Miocárdio/química; Oxigênio/farmacologia; Proteínas/análise; Proteínas/efeitos dos fármacos; Proteoma/efeitos dos fármacos; Proteoma/metabolismo

Palavras-chave

cardiac fibroblast; cardiovascular; exosome; paracrine factors; secretome

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fibroblastos / Hipóxia / Miocárdio Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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