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Ligand- and Solvent-Tuned Chemoselective Carbonylation of Bromoaryl Triflates.
Shen, Chaoren; Wei, Zhihong; Jiao, Haijun; Wu, Xiao-Feng.
Afiliação
  • Shen C; Leibniz-Institut für Katalyse e.V., Universität Rostock, Albert-Einstein-Strasse 29a, 18059, Rostock, Germany.
  • Wei Z; Leibniz-Institut für Katalyse e.V., Universität Rostock, Albert-Einstein-Strasse 29a, 18059, Rostock, Germany.
  • Jiao H; Leibniz-Institut für Katalyse e.V., Universität Rostock, Albert-Einstein-Strasse 29a, 18059, Rostock, Germany.
  • Wu XF; Leibniz-Institut für Katalyse e.V., Universität Rostock, Albert-Einstein-Strasse 29a, 18059, Rostock, Germany.
Chemistry ; 23(54): 13369-13378, 2017 Sep 27.
Article em En | MEDLINE | ID: mdl-28650074
The palladium-catalyzed chemoselective carbonylation of bromoaryl triflates is reported. The selective C-Br bond versus C-OTf (OTf=triflate) bond functionalization can be remarkably tuned by the combination of the ligand [4,5-bis(diphenylphosphino)-9,9-dimethylxanthene (Xantphos) vs. 1,1'-bis(diphenylphosphino)ferrocene (DPPF)] and the solvent (toluene vs. DMSO). The respective ligand and solvent effects are rationalized by DFT calculations. In contrast, the monodentate ligands BuPAd2 and tBu3 P prefer the selective C-Br bond activation and are solvent insensitive.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article