Omega-3 polyunsaturated fatty acids ameliorates testicular ischemia-reperfusion injury through the induction of Nrf2 and inhibition of NF-&#954;B in rats.

Qi, Xiaokang; Qin, Zhiqiang; Tang, Jingyuan; Han, Peng; Xing, Qianwei; Wang, Kunpeng; Yu, Junjie; Zhou, Guangchen; Tang, Min; Wang, Wei; Zhang, Wei

Omega-3 polyunsaturated fatty acids ameliorates testicular ischemia-reperfusion injury through the induction of Nrf2 and inhibition of NF-κB in rats.

Qi, Xiaokang; Qin, Zhiqiang; Tang, Jingyuan; Han, Peng; Xing, Qianwei; Wang, Kunpeng; Yu, Junjie; Zhou, Guangchen; Tang, Min; Wang, Wei; Zhang, Wei.

Afiliação

Qi X; Department of Urology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China; Department of Urology, Subei People's Hospital, Yangzhou 225000, China.
Qin Z; Department of Urology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Tang J; Department of Urology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Han P; Department of Urology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Xing Q; Department of Urology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China; Department of Urology, Affiliated Hospital of Nantong University, Nantong 226001, China.
Wang K; Department of Urology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China; Department of Urology, First People's Hospital of Lianyungang City, Lianyungang 222002, China.
Yu J; Department of Urology, Subei People's Hospital, Yangzhou 225000, China.
Zhou G; Department of Urology, Subei People's Hospital, Yangzhou 225000, China.
Tang M; Department of Urology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Wang W; Department of Urology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Zhang W; Department of Urology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Electronic address: zhangwei_urology@sina.com.

Exp Mol Pathol ; 103(1): 44-50, 2017 08.

Article em En | MEDLINE | ID: mdl-28655519

Assuntos

Ácidos Graxos Ômega-3/farmacologia; Fator 2 Relacionado a NF-E2/metabolismo; NF-kappa B/metabolismo; Traumatismo por Reperfusão/tratamento farmacológico; Testículo/efeitos dos fármacos; Animais; Biomarcadores/sangue; Regulação da Expressão Gênica; Glutationa/metabolismo; Heme Oxigenase-1/genética; Heme Oxigenase-1/metabolismo; Masculino; Malondialdeído/sangue; NAD(P)H Desidrogenase (Quinona)/genética; NAD(P)H Desidrogenase (Quinona)/metabolismo; Fator 2 Relacionado a NF-E2/genética; NF-kappa B/genética; Estresse Oxidativo/efeitos dos fármacos; Ratos; Ratos Sprague-Dawley; Superóxido Dismutase/genética; Superóxido Dismutase/metabolismo; Testículo/metabolismo

Palavras-chave

Ischemia and reperfusion injury; Nuclear transcription factor erythroid 2-related factor 2; Omega-3 polyunsaturated fatty acids; Oxidative stress

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Testículo / Traumatismo por Reperfusão / Ácidos Graxos Ômega-3 / NF-kappa B / Fator 2 Relacionado a NF-E2 Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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