A time for promiscuity in a eukaryotic recombinase.
J Biol Chem
; 292(26): 11136-11137, 2017 06 30.
Article
em En
| MEDLINE
| ID: mdl-28667173
ABSTRACT
The exchange of DNA strands between broken and intact molecules lies at the heart of fundamental cellular processes ranging from repairing DNA damage by homologous recombination to generation of genetic diversity during sexual reproduction. New work by Lee and colleagues utilizes the DNA curtain method, an elegant single-molecule technique, to demonstrate common and idiosyncratic features in the DNA strand exchange mechanisms of three RecA-family recombinases, bacterial RecA, and eukaryotic Rad51 and Dmc1 proteins.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Recombinases Rec A
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Saccharomyces cerevisiae
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Bactérias
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Proteínas de Bactérias
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Proteínas de Ciclo Celular
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Proteínas de Saccharomyces cerevisiae
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Proteínas de Ligação a DNA
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Reparo do DNA
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Rad51 Recombinase
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article