Rare progerin-expressing preadipocytes and adipocytes contribute to tissue depletion over time.

Revêchon, Gwladys; Viceconte, Nikenza; McKenna, Tomás; Sola Carvajal, Agustín; Vrtacnik, Peter; Stenvinkel, Peter; Lundgren, Torbjörn; Hultenby, Kjell; Franco, Irene; Eriksson, Maria

Revêchon, Gwladys; Viceconte, Nikenza; McKenna, Tomás; Sola Carvajal, Agustín; Vrtacnik, Peter; Stenvinkel, Peter; Lundgren, Torbjörn; Hultenby, Kjell; Franco, Irene; Eriksson, Maria.

Afiliação

Revêchon G; Department of Biosciences and Nutrition, Karolinska Institutet, 14183, Huddinge, Sweden.
Viceconte N; Department of Biosciences and Nutrition, Karolinska Institutet, 14183, Huddinge, Sweden.
McKenna T; Department of Biosciences and Nutrition, Karolinska Institutet, 14183, Huddinge, Sweden.
Sola Carvajal A; Department of Biosciences and Nutrition, Karolinska Institutet, 14183, Huddinge, Sweden.
Vrtacnik P; Department of Biosciences and Nutrition, Karolinska Institutet, 14183, Huddinge, Sweden.
Stenvinkel P; Department of Clinical Science, Intervention and Technology, Division of Renal Medicine, Karolinska Institutet, 14186, Stockholm, Sweden.
Lundgren T; Department of Clinical Science, Intervention and Technology, Division of Transplantation Surgery, Karolinska Institutet, 14186, Stockholm, Sweden.
Hultenby K; Department of Laboratory Medicine, Karolinska Institutet, 14183, Stockholm, Sweden.
Franco I; Department of Biosciences and Nutrition, Karolinska Institutet, 14183, Huddinge, Sweden.
Eriksson M; Department of Biosciences and Nutrition, Karolinska Institutet, 14183, Huddinge, Sweden. Maria.Eriksson.2@ki.se.

Sci Rep ; 7(1): 4405, 2017 06 30.

Article em En | MEDLINE | ID: mdl-28667315

Assuntos

Adipócitos/metabolismo; Tecido Adiposo Branco/metabolismo; Lamina Tipo A/genética; Progéria/genética; Tecido Adiposo Branco/patologia; Fatores Etários; Animais; Morte Celular; Proliferação de Células; Dano ao DNA; Expressão Gênica; Humanos; Inflamação/genética; Inflamação/metabolismo; Inflamação/patologia; Lamina Tipo A/metabolismo; Macrófagos/metabolismo; Macrófagos/patologia; Camundongos; Camundongos Transgênicos; Modelos Biológicos; Progéria/metabolismo; Progéria/patologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Progéria / Adipócitos / Lamina Tipo A / Tecido Adiposo Branco Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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