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Sirtuin 3 rescues neurons through the stabilisation of mitochondrial biogenetics in the virally-expressing mutant α-synuclein rat model of parkinsonism.
Gleave, Jacqueline A; Arathoon, Lindsay R; Trinh, Dennison; Lizal, Kristin E; Giguère, Nicolas; Barber, James H M; Najarali, Zainab; Khan, M Hassan; Thiele, Sherri L; Semmen, Mahin S; Koprich, James B; Brotchie, Jonathan M; Eubanks, James H; Trudeau, Louis-Eric; Nash, Joanne E.
Afiliação
  • Gleave JA; Centre for the Neurobiology of Stress, Department of Biological Sciences, University of Toronto Scarborough, Toronto, Ontario, Canada.
  • Arathoon LR; Centre for the Neurobiology of Stress, Department of Biological Sciences, University of Toronto Scarborough, Toronto, Ontario, Canada.
  • Trinh D; Centre for the Neurobiology of Stress, Department of Biological Sciences, University of Toronto Scarborough, Toronto, Ontario, Canada.
  • Lizal KE; Centre for the Neurobiology of Stress, Department of Biological Sciences, University of Toronto Scarborough, Toronto, Ontario, Canada.
  • Giguère N; Department of Pharmacology, Central Nervous System Research Group (GRSNC), Faculty of Medicine, Universite de Montreal, Montreal, Quebec, Canada; Department Neuroscience, Central Nervous System Research Group (GRSNC), Faculty of Medicine, Universite de Montreal, Montreal, Quebec, Canada.
  • Barber JHM; Centre for the Neurobiology of Stress, Department of Biological Sciences, University of Toronto Scarborough, Toronto, Ontario, Canada.
  • Najarali Z; Centre for the Neurobiology of Stress, Department of Biological Sciences, University of Toronto Scarborough, Toronto, Ontario, Canada.
  • Khan MH; Centre for the Neurobiology of Stress, Department of Biological Sciences, University of Toronto Scarborough, Toronto, Ontario, Canada.
  • Thiele SL; Centre for the Neurobiology of Stress, Department of Biological Sciences, University of Toronto Scarborough, Toronto, Ontario, Canada.
  • Semmen MS; Centre for the Neurobiology of Stress, Department of Biological Sciences, University of Toronto Scarborough, Toronto, Ontario, Canada.
  • Koprich JB; Krembil Research Institute, Toronto Western Hospital, Toronto, Ontario, Canada.
  • Brotchie JM; Krembil Research Institute, Toronto Western Hospital, Toronto, Ontario, Canada.
  • Eubanks JH; Krembil Research Institute, Toronto Western Hospital, Toronto, Ontario, Canada.
  • Trudeau LE; Department of Pharmacology, Central Nervous System Research Group (GRSNC), Faculty of Medicine, Universite de Montreal, Montreal, Quebec, Canada; Department Neuroscience, Central Nervous System Research Group (GRSNC), Faculty of Medicine, Universite de Montreal, Montreal, Quebec, Canada.
  • Nash JE; Centre for the Neurobiology of Stress, Department of Biological Sciences, University of Toronto Scarborough, Toronto, Ontario, Canada. Electronic address: jnash@utsc.utoronto.ca.
Neurobiol Dis ; 106: 133-146, 2017 Oct.
Article em En | MEDLINE | ID: mdl-28673739
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtornos Parkinsonianos / Alfa-Sinucleína / Sirtuína 3 / Neuroproteção / Mitocôndrias / Neurônios Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtornos Parkinsonianos / Alfa-Sinucleína / Sirtuína 3 / Neuroproteção / Mitocôndrias / Neurônios Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2017 Tipo de documento: Article