[Persistent neurological syndrome after treatment with lithium salts. Toxicity of the lithium-neuroleptic combination?]. / Syndrome neurologique persistant après traitement par les sels de lithium. Toxicité de l'association lithium-neuroleptiques?

ABSTRACT

In 2 patients receiving a long-term lithium carbonate therapy, persistent cerebellar, pyramidal, and extrapyramidal signs were observed, following a febrile pulmonary event. The mechanism of these disturbances is discussed, emphasizing the lithium-neuroleptics interaction as well as the possible role of hyperthermia.