Anti-Markovnikov Hydrofunctionalization of Alkenes: Use of a Benzyl Group as a Traceless Redox-Active Hydrogen Donor.
Angew Chem Int Ed Engl
; 56(38): 11440-11444, 2017 09 11.
Article
em En
| MEDLINE
| ID: mdl-28722345
A protocol for the anti-Markovnikov hydrofunctionalization of alkenes has been developed by the use of a benzyl group as a traceless redox-active hydrogen donor. Under copper catalysis and in the presence of CF3 - or N3 -containing hypervalent iodine reagents, a series of homoallylic alcohol derivatives were hydrofunctionalized regioselectivity. A similar principle was also applied to the hydrofunctionalization of alkenols.
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01-internacional
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MEDLINE
Idioma:
En
Ano de publicação:
2017
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Article