Pharmacologic modeling of primary mitochondrial respiratory chain dysfunction in zebrafish.

Byrnes, James; Ganetzky, Rebecca; Lightfoot, Richard; Tzeng, Michael; Nakamaru-Ogiso, Eiko; Seiler, Christoph; Falk, Marni J

Byrnes, James; Ganetzky, Rebecca; Lightfoot, Richard; Tzeng, Michael; Nakamaru-Ogiso, Eiko; Seiler, Christoph; Falk, Marni J.

Afiliação

Byrnes J; Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, United States.
Ganetzky R; Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, United States.
Lightfoot R; Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, United States.
Tzeng M; Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, United States.
Nakamaru-Ogiso E; Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, United States.
Seiler C; Aquatics Core Facility, The Children's Hospital of Philadelphia Research Institute, Philadelphia, PA 19104, United States.
Falk MJ; Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, United States; Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, United States. Electronic address: falkm@email.chop.edu.

Neurochem Int ; 117: 23-34, 2018 07.

Article em En | MEDLINE | ID: mdl-28732770

Assuntos

Complexo de Proteínas da Cadeia de Transporte de Elétrons/antagonistas & inibidores; Complexo de Proteínas da Cadeia de Transporte de Elétrons/metabolismo; Mitocôndrias/efeitos dos fármacos; Mitocôndrias/metabolismo; Rotenona/farmacologia; Azida Sódica/farmacologia; Animais; Inibidores Enzimáticos/farmacologia; Inseticidas/farmacologia; Peixe-Zebra

Palavras-chave

Chloramphenicol (PubChem CID: 5959); Complex I; Complex IV; Complex V; D. rerio; Mitochondrial translation; Mitotracker green FM (PubChem CID: 59705974); Oligomycin (PubChem CID: 16760598); Probucol (PubChem CID: 4912); Rotenone (PubChem CID: 6758); Sodium azide (PubChem CID: 33557); TMRE (PubChem CID: 2762682)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Rotenona / Azida Sódica / Complexo de Proteínas da Cadeia de Transporte de Elétrons / Mitocôndrias Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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