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Potential peptidic proteasome inhibitors by incorporation of an electrophilic trap based on amino acid derived α-substituted sulfonyl fluorides.
Herrero Alvarez, Natalia; van de Langemheen, Helmus; Brouwer, Arwin J; Liskamp, Rob M J.
Afiliação
  • Herrero Alvarez N; School of Chemistry, Joseph Black Building, University of Glasgow, University Avenue, Glasgow G12 8QQ, UK.
  • van de Langemheen H; School of Chemistry, Joseph Black Building, University of Glasgow, University Avenue, Glasgow G12 8QQ, UK.
  • Brouwer AJ; Chemical Biology & Drug Discovery, Department of Pharmaceutical Sciences, Faculty of Science, Utrecht University, PO Box 80082, 3508 TB Utrecht, The Netherlands.
  • Liskamp RMJ; School of Chemistry, Joseph Black Building, University of Glasgow, University Avenue, Glasgow G12 8QQ, UK; Chemical Biology & Drug Discovery, Department of Pharmaceutical Sciences, Faculty of Science, Utrecht University, PO Box 80082, 3508 TB Utrecht, The Netherlands. Electronic address: robert.
Bioorg Med Chem ; 25(19): 5055-5063, 2017 10 01.
Article em En | MEDLINE | ID: mdl-28734665
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácidos Sulfínicos / Desenho de Fármacos / Peptidomiméticos / Inibidores de Proteassoma Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácidos Sulfínicos / Desenho de Fármacos / Peptidomiméticos / Inibidores de Proteassoma Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article